@article{ed8ddd431eac4eeebaea54447d1d8373,
title = "Alkenylazaarenes as dipolarophiles in 1,3-dipolar cycloaddition of nitrones: Regioselectivity-switchable and highly diastereoselective synthesis of multisubstituted isoxazolidines",
abstract = "Alkenylazaarenes as a novel class of dipolarophiles for 1,3-dipolar cycloaddition (1,3-DC) with nitrones was reported. A regioselectivity-switchable synthesis of multisubstituted isoxazolidines had been developed. In the presence of TMSOTf as catalyst, 4-substituted isoxazolidines were obtained as major products with high regio- and diastereoselectivities. Nonetheless, under microwave irradiation in a sealed system with water as solvent, exclusive 5-substituted isoxazolidines were produced in good yields.",
author = "Mengchao Tong and Yong Zhang and Cong Qin and Yiwei Fu and Yonghai Liu and Hao Li and Wei Wang",
note = "Funding Information: This work was supported by the National Natural Science Foundation of China (21572055, 21738002 and 21572054), the program for Professor of Special Appointment (Eastern Scholar) at Shanghai Institutions of Higher Learning, the Fundamental Research Funds for the Central Universities and the China 111 Project (Grant B07023). Publisher Copyright: {\textcopyright} the Partner Organisations.",
year = "2018",
month = oct,
day = "21",
doi = "10.1039/c8qo00826d",
language = "English (US)",
volume = "5",
pages = "2945--2949",
journal = "Organic Chemistry Frontiers",
issn = "2052-4110",
publisher = "Royal Society of Chemistry",
number = "20",
}