Airway response to inhaled histamine in asymptomatic long-term marijuana smokers

Manuel J. Hernandez, Fernando Martinez, H. Thomas Blair, Warren C. Miller

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Bronchial challenge with histamine was used to assess bronchial reactivity in asymptomatic individuals who were long-term social smokers of marijuana. Their reactivity was compared to that of nonsmokers and asthmatics. Spirometry results were normal in the marijuana users. There was no significant difference in bronchial reactivity between marijuana smokers and nonsmoking controls, whereas the asthmatics demonstrated the expected hyperreactivity. These observations suggest that customary social use of marijuana may not produce abnormalities in airway function detectable by spirometry or bronchoprovocation.

Original languageEnglish (US)
Pages (from-to)153-155
Number of pages3
JournalThe Journal of Allergy and Clinical Immunology
Issue number2
StatePublished - Feb 1981

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology


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