Abstract
A hypothesis is presented to explain the link between acquired immunodeficiency syndrome (AIDS) and Kaposi's sarcoma (KS). According to this hypothesis, AIDS involves all four components of the integrated lymphatic system-lymphatics, lymph nodes, lymphocytes, and lymph- and thereby resembles various congenital and acquired lymphologic syndromes characterized by one or more of the following features: lymphostasis, angiogenesis, and fibrosis; depletion of immunocompetent cells and immunosuppression; opportunistic infections; and vascular neoplasms. A better understanding of the steps in the evolution of these processes and their interrelationships to the four components of the lymphatic system should provide insight into the immunopathogenesis of AIDS-KS as well as its detection and treatment.
Original language | English (US) |
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Pages (from-to) | 4-10 |
Number of pages | 7 |
Journal | Lymphology |
Volume | 21 |
Issue number | 1 |
State | Published - 1988 |
ASJC Scopus subject areas
- Immunology and Allergy
- Hematology