Advanced cardiac life support training improves long-term survival from in-hospital cardiac arrest

Miguel Antonio Moretti, Luiz Antonio Machado Cesar, Amit Nusbacher, Karl B. Kern, Sergio Timerman, José Antonio Franchini Ramires

Research output: Contribution to journalArticlepeer-review

107 Scopus citations


Context: Advanced cardiac life support (ACLS) training was introduced to bring order and a systematic approach to the treatment of cardiac arrest by professional responders. In spite of the wide dissemination of ACLS training, it has been difficult to demonstrate improved outcome following such training. Objective: To determine the value of formal ACLS training in improving survival from in-hospital cardiac arrest. Design, setting, and participants: A multi-center, prospective cohort study examined patient outcomes after resuscitation efforts by in-hospital rescue teams with and without ACLS-trained personnel. A total of 156 patients, experiencing 172 in-hospital cardiopulmonary arrest events over a 38-month period (January 1998 to March 2001) were studied. Main outcome measures: Primary endpoints included return of spontaneous circulation (ROSC), survival to hospital discharge, 30-day survival, and 1-year survival. Results: The immediate success of resuscitation efforts for all patients was 39.7% (62/156). There was a significant increase in ROSC with ACLS-trained personnel (49/113; 43.4%) versus no ALCS-trained personnel (16/59; 27.1%; p = 0.04). Likewise, patients treated by ACLS-trained personnel had increased survival to hospital discharge (26/82; 31.7% versus 7/34; 20.6%; p = 0.23), significantly better 30-day survival (22/82; 26.8% versus 2/34; 5.9%; p < 0.02), and significantly improved 1-year survival (18/82; 21.9% versus 0/34; 0%; p < 0.002). Conclusion: The presence of at least one ACLS-trained team member at in-hospital resuscitation efforts increases both short and long-term survival following cardiac arrest.

Original languageEnglish (US)
Pages (from-to)458-465
Number of pages8
Issue number3
StatePublished - Mar 2007


  • 'In-hospital Utstein'
  • 1-Year survival after cardiac arrest
  • Advanced cardiac life support (ACLS)
  • Cardiac arrest
  • Cardiopulmonary resuscitation (CPR)

ASJC Scopus subject areas

  • Emergency Medicine
  • Emergency
  • Cardiology and Cardiovascular Medicine


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