Adjuvant immunotherapy with bacillus Calmette-Guérin in prostatic cancer

P. Guinan; G. Baumgartner; E. Totonchi; T. John; R. Crispen; R. Rao; R. Ablin

doi:10.1016/0090-4295(79)90523-5

Adjuvant immunotherapy with bacillus Calmette-Guérin in prostatic cancer

P. Guinan, G. Baumgartner, E. Totonchi, T. John, R. Crispen, R. Rao, R. Ablin

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Ninety-two patients with histologically proved prostatic cancer were studied. Forty-six patients were treated with bacillus Calmette-Guerin (BCG) adjuvant immunotherapy, and 46 other patients, matched for stage and hormone therapy, served as controls. Survival from the time of histologic diagnosis was sixteen and one-half months longer (thirty-seven and one-half versus twenty-one months) in the BCG-treated patients. There was no mortality and only minimal morbidity. Changes in some immunologic parameters (white blood cell count, skin tests) suggest an immune response.

Original language	English (US)
Pages (from-to)	561-565
Number of pages	5
Journal	Urology
Volume	14
Issue number	6
DOIs	https://doi.org/10.1016/0090-4295(79)90523-5
State	Published - Dec 1979
Externally published	Yes

ASJC Scopus subject areas

Urology

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AU - Totonchi, E.

AU - John, T.

AU - Crispen, R.

AU - Rao, R.

AU - Ablin, R.

PY - 1979/12

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N2 - Ninety-two patients with histologically proved prostatic cancer were studied. Forty-six patients were treated with bacillus Calmette-Guerin (BCG) adjuvant immunotherapy, and 46 other patients, matched for stage and hormone therapy, served as controls. Survival from the time of histologic diagnosis was sixteen and one-half months longer (thirty-seven and one-half versus twenty-one months) in the BCG-treated patients. There was no mortality and only minimal morbidity. Changes in some immunologic parameters (white blood cell count, skin tests) suggest an immune response.

AB - Ninety-two patients with histologically proved prostatic cancer were studied. Forty-six patients were treated with bacillus Calmette-Guerin (BCG) adjuvant immunotherapy, and 46 other patients, matched for stage and hormone therapy, served as controls. Survival from the time of histologic diagnosis was sixteen and one-half months longer (thirty-seven and one-half versus twenty-one months) in the BCG-treated patients. There was no mortality and only minimal morbidity. Changes in some immunologic parameters (white blood cell count, skin tests) suggest an immune response.

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Adjuvant immunotherapy with bacillus Calmette-Guérin in prostatic cancer

Abstract

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