Adaptive SPECT

Harrison H Barrett; Lars R. Furenlid; Melanie Freed; Jacob Y. Hesterman; Matthew A. Kupinski; Eric W Clarkson; Meredith K. Whitaker

doi:10.1109/TMI.2007.913241

Adaptive SPECT

Harrison H Barrett, Lars R. Furenlid, Melanie Freed, Jacob Y. Hesterman, Matthew A. Kupinski, Eric W Clarkson, Meredith K. Whitaker

Research output: Contribution to journal › Article › peer-review

80 Scopus citations

Abstract

Adaptive imaging systems alter their data-acquisition configuration or protocol in response to the image information received. An adaptive pinhole single-photon emission computed tomography (SPECT) system might acquire an initial scout image to obtain preliminary information about the radiotracer distribution and then adjust the configuration or sizes of the pinholes, the magnifications, or the projection angles in order to improve performance. This paper briefly describes two small-animal SPECT systems that allow this flexibility and then presents a framework for evaluating adaptive systems in general, and adaptive SPECT systems in particular. The evaluation is in terms of the performance of linear observers on detection or estimation tasks. Expressions are derived for the ideal linear (Hotelling) observer and the ideal linear (Wiener) estimator with adaptive imaging. Detailed expressions for the performance figures of merit are given, and possible adaptation rules are discussed.

Original language	English (US)
Article number	4389806
Pages (from-to)	775-788
Number of pages	14
Journal	IEEE Transactions on Medical Imaging
Volume	27
Issue number	6
DOIs	https://doi.org/10.1109/TMI.2007.913241
State	Published - Jun 2008

Keywords

Adaptive imaging
Hotelling observer
Image quality
Single-photon emission computed tomography (SPECT)
Wiener estimator

ASJC Scopus subject areas

Software
Radiological and Ultrasound Technology
Computer Science Applications
Electrical and Electronic Engineering

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10.1109/TMI.2007.913241

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title = "Adaptive SPECT",

abstract = "Adaptive imaging systems alter their data-acquisition configuration or protocol in response to the image information received. An adaptive pinhole single-photon emission computed tomography (SPECT) system might acquire an initial scout image to obtain preliminary information about the radiotracer distribution and then adjust the configuration or sizes of the pinholes, the magnifications, or the projection angles in order to improve performance. This paper briefly describes two small-animal SPECT systems that allow this flexibility and then presents a framework for evaluating adaptive systems in general, and adaptive SPECT systems in particular. The evaluation is in terms of the performance of linear observers on detection or estimation tasks. Expressions are derived for the ideal linear (Hotelling) observer and the ideal linear (Wiener) estimator with adaptive imaging. Detailed expressions for the performance figures of merit are given, and possible adaptation rules are discussed.",

keywords = "Adaptive imaging, Hotelling observer, Image quality, Single-photon emission computed tomography (SPECT), Wiener estimator",

author = "Barrett, {Harrison H} and Furenlid, {Lars R.} and Melanie Freed and Hesterman, {Jacob Y.} and Kupinski, {Matthew A.} and Clarkson, {Eric W} and Whitaker, {Meredith K.}",

note = "Funding Information: Manuscript received August 16, 2007; revised November 12, 2007. This work was supported by the National Institutes of Health under Grant P41 EB 002035 and Grant R37 EB 000803. Asterisk indicates corresponding author. *H. H. Barrett is with the Center for Gamma-Ray Imaging and the Department of Radiology, University of Arizona, Tucson, AZ 85724 USA and also with the College of Optical Sciences, University of Arizona, Tucson, AZ 85721 USA (e-mail: [email protected]).",

year = "2008",

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language = "English (US)",

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AU - Freed, Melanie

AU - Hesterman, Jacob Y.

AU - Kupinski, Matthew A.

AU - Clarkson, Eric W

AU - Whitaker, Meredith K.

N1 - Funding Information: Manuscript received August 16, 2007; revised November 12, 2007. This work was supported by the National Institutes of Health under Grant P41 EB 002035 and Grant R37 EB 000803. Asterisk indicates corresponding author. *H. H. Barrett is with the Center for Gamma-Ray Imaging and the Department of Radiology, University of Arizona, Tucson, AZ 85724 USA and also with the College of Optical Sciences, University of Arizona, Tucson, AZ 85721 USA (e-mail: [email protected]).

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Adaptive SPECT

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Keywords

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