Acute respiratory failure and diffuse pulmonary infiltrates four weeks after rituximab therapy

Hadi H. Hatoum; George A. Sarosi; Kenneth S. Knox; Chadi A. Hage

doi:10.1016/j.rmedc.2008.12.004

Acute respiratory failure and diffuse pulmonary infiltrates four weeks after rituximab therapy

Hadi H. Hatoum, George A. Sarosi, Kenneth S. Knox, Chadi A. Hage

Research output: Contribution to journal › Article › peer-review

Abstract

We report a 51-year-old woman with known SLE on low dose prednisone, recently started on rituximab, who presents with acute respiratory failure and bilateral air space disease. After an initial treatment with broad spectrum antibiotics for healthcare-associated pneumonia and negative serologic studies, a diagnosis of pneumocystis pneumonia was established using bronchoalveolar lavage. We suggest that rituximab can be an aggravating cause of pneumocystis in patients treated with prednisone.

Original language	English (US)
Pages (from-to)	134-136
Number of pages	3
Journal	Respiratory Medicine CME
Volume	2
Issue number	3
DOIs	https://doi.org/10.1016/j.rmedc.2008.12.004
State	Published - 2009

Keywords

Pneumocystis pneumonia
Rituximab

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine

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10.1016/j.rmedc.2008.12.004

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title = "Acute respiratory failure and diffuse pulmonary infiltrates four weeks after rituximab therapy",

abstract = "We report a 51-year-old woman with known SLE on low dose prednisone, recently started on rituximab, who presents with acute respiratory failure and bilateral air space disease. After an initial treatment with broad spectrum antibiotics for healthcare-associated pneumonia and negative serologic studies, a diagnosis of pneumocystis pneumonia was established using bronchoalveolar lavage. We suggest that rituximab can be an aggravating cause of pneumocystis in patients treated with prednisone.",

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AU - Hatoum, Hadi H.

AU - Sarosi, George A.

AU - Knox, Kenneth S.

AU - Hage, Chadi A.

PY - 2009

Y1 - 2009

N2 - We report a 51-year-old woman with known SLE on low dose prednisone, recently started on rituximab, who presents with acute respiratory failure and bilateral air space disease. After an initial treatment with broad spectrum antibiotics for healthcare-associated pneumonia and negative serologic studies, a diagnosis of pneumocystis pneumonia was established using bronchoalveolar lavage. We suggest that rituximab can be an aggravating cause of pneumocystis in patients treated with prednisone.

AB - We report a 51-year-old woman with known SLE on low dose prednisone, recently started on rituximab, who presents with acute respiratory failure and bilateral air space disease. After an initial treatment with broad spectrum antibiotics for healthcare-associated pneumonia and negative serologic studies, a diagnosis of pneumocystis pneumonia was established using bronchoalveolar lavage. We suggest that rituximab can be an aggravating cause of pneumocystis in patients treated with prednisone.

KW - Pneumocystis pneumonia

KW - Rituximab

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ER -

Acute respiratory failure and diffuse pulmonary infiltrates four weeks after rituximab therapy

Abstract

Keywords

ASJC Scopus subject areas

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