Acute Kidney Injury

Remigio J. Flor, Keneeshia N. Williams, Terence O'Keeffe

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations


This is a unique question-and-answer chapter for surgical residents and trainees, concentrating on the acute kidney injury (AKI). The term acute renal failure (ARF) has been largely replaced by AKI. AKI is considered a more accurate description of an acute loss of kidney function that is of clinical relevance but that does not necessarily result in overt organ failure. A patient who has a urine output of less than 0.5mL/kg/hour for 6 hours is one of the Kidney Disease: Improving Global Outcomes (KDIGO) criteria for defining AKI. This patient classifies as stage 1 AKI. A serum creatinine increase of 2 times over baseline the past 48 hours meets the KDIGO criteria of 2.0-2.9 times increase from baseline for stage 2 AKI. Furthermore, anuria for at least 12 hours meets the definition of stage 3 AKI. The KDIGO criteria uses only changes in the biomarkers of serum creatinine and urine output for adults.

Original languageEnglish (US)
Title of host publicationSurgical Critical Care and Emergency Surgery
Subtitle of host publicationClinical Questions and Answers: Second Edition
Number of pages9
ISBN (Electronic)9781119317913
ISBN (Print)9781119317920
StatePublished - Apr 3 2018


  • Acute kidney injury
  • Acute renal failure
  • Anuria
  • KDIGO criteria
  • Serum creatinine

ASJC Scopus subject areas

  • General Medicine


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