Acute and chronic morphine effects on plasma corticosteroids and growth hormone in the cat

Edward D. French; Joseph F. Garcia; Robert George

doi:10.1016/0306-4530(78)90014-8

Acute and chronic morphine effects on plasma corticosteroids and growth hormone in the cat

Edward D. French, Joseph F. Garcia, Robert George

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

(1) Low doses of intravenous morphine in the cat caused an elevation of both corticosteroid and growth hormone in plasma. (2) Corticosteroid levels did not continue to increase in concert with the dose of morphine but the level of growth hormone did. (3) Tolerance developed to the effects of morphine on corticosteroids but not to the effect on growth hormone. (4) Naloxone precipitated withdrawal was associated with an increase in plasma corticosteroid but not growth hormone.

Original language	English (US)
Pages (from-to)	237-244
Number of pages	8
Journal	Psychoneuroendocrinology
Volume	3
Issue number	3-4
DOIs	https://doi.org/10.1016/0306-4530(78)90014-8
State	Published - Oct 1978
Externally published	Yes

Keywords

cat
corticosteroids
growth hormone
morphine

ASJC Scopus subject areas

Endocrinology, Diabetes and Metabolism
Endocrinology
Endocrine and Autonomic Systems
Psychiatry and Mental health
Biological Psychiatry

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10.1016/0306-4530(78)90014-8

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title = "Acute and chronic morphine effects on plasma corticosteroids and growth hormone in the cat",

abstract = "(1) Low doses of intravenous morphine in the cat caused an elevation of both corticosteroid and growth hormone in plasma. (2) Corticosteroid levels did not continue to increase in concert with the dose of morphine but the level of growth hormone did. (3) Tolerance developed to the effects of morphine on corticosteroids but not to the effect on growth hormone. (4) Naloxone precipitated withdrawal was associated with an increase in plasma corticosteroid but not growth hormone.",

keywords = "cat, corticosteroids, growth hormone, morphine",

author = "French, {Edward D.} and Garcia, {Joseph F.} and Robert George",

note = "Funding Information: We wish to thank Endo Laboratories, Inc. for their generous supply of naloxone. We also thank Mr. Secgio Vasquez for his valuable laboratory assistance. This work was supported by USPHS Grant DA-01006.",

year = "1978",

month = oct,

doi = "10.1016/0306-4530(78)90014-8",

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pages = "237--244",

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T1 - Acute and chronic morphine effects on plasma corticosteroids and growth hormone in the cat

AU - French, Edward D.

AU - Garcia, Joseph F.

AU - George, Robert

N1 - Funding Information: We wish to thank Endo Laboratories, Inc. for their generous supply of naloxone. We also thank Mr. Secgio Vasquez for his valuable laboratory assistance. This work was supported by USPHS Grant DA-01006.

PY - 1978/10

Y1 - 1978/10

N2 - (1) Low doses of intravenous morphine in the cat caused an elevation of both corticosteroid and growth hormone in plasma. (2) Corticosteroid levels did not continue to increase in concert with the dose of morphine but the level of growth hormone did. (3) Tolerance developed to the effects of morphine on corticosteroids but not to the effect on growth hormone. (4) Naloxone precipitated withdrawal was associated with an increase in plasma corticosteroid but not growth hormone.

AB - (1) Low doses of intravenous morphine in the cat caused an elevation of both corticosteroid and growth hormone in plasma. (2) Corticosteroid levels did not continue to increase in concert with the dose of morphine but the level of growth hormone did. (3) Tolerance developed to the effects of morphine on corticosteroids but not to the effect on growth hormone. (4) Naloxone precipitated withdrawal was associated with an increase in plasma corticosteroid but not growth hormone.

KW - cat

KW - corticosteroids

KW - growth hormone

KW - morphine

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IS - 3-4

ER -

Acute and chronic morphine effects on plasma corticosteroids and growth hormone in the cat

Abstract

Keywords

ASJC Scopus subject areas

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