Activity-based high-throughput profiling of metalloprotease inhibitors using small molecule microarrays

Jun Wang; Mahesh Uttamchandani; Ping Sun Li; Shao Q. Yao

doi:10.1039/b515278j

Activity-based high-throughput profiling of metalloprotease inhibitors using small molecule microarrays

Jun Wang
, Mahesh Uttamchandani
, Ping Sun Li
, Shao Q. Yao

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Abstract

We herein describe a high-throughput small molecule microarray (SMM) method that enables quick and cost-effective identification of potent inhibitors of metalloproteases in an activity-dependent manner, thereby offering a rapid means for inhibitor discovery and profiling.

Original language	English (US)
Pages (from-to)	717-719
Number of pages	3
Journal	Chemical Communications
Issue number	7
DOIs	https://doi.org/10.1039/b515278j
State	Published - 2006
Externally published	Yes

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/b515278j

Cite this

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title = "Activity-based high-throughput profiling of metalloprotease inhibitors using small molecule microarrays",

abstract = "We herein describe a high-throughput small molecule microarray (SMM) method that enables quick and cost-effective identification of potent inhibitors of metalloproteases in an activity-dependent manner, thereby offering a rapid means for inhibitor discovery and profiling.",

author = "Jun Wang and Mahesh Uttamchandani and Li, \{Ping Sun\} and Yao, \{Shao Q.\}",

year = "2006",

doi = "10.1039/b515278j",

language = "English (US)",

pages = "717--719",

journal = "Chemical Communications",

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T1 - Activity-based high-throughput profiling of metalloprotease inhibitors using small molecule microarrays

AU - Wang, Jun

AU - Uttamchandani, Mahesh

AU - Li, Ping Sun

AU - Yao, Shao Q.

PY - 2006

Y1 - 2006

N2 - We herein describe a high-throughput small molecule microarray (SMM) method that enables quick and cost-effective identification of potent inhibitors of metalloproteases in an activity-dependent manner, thereby offering a rapid means for inhibitor discovery and profiling.

AB - We herein describe a high-throughput small molecule microarray (SMM) method that enables quick and cost-effective identification of potent inhibitors of metalloproteases in an activity-dependent manner, thereby offering a rapid means for inhibitor discovery and profiling.

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UR - https://www.scopus.com/pages/publications/32644481005#tab=citedBy

U2 - 10.1039/b515278j

DO - 10.1039/b515278j

M3 - Article

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AN - SCOPUS:32644481005

SN - 1359-7345

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EP - 719

JO - Chemical Communications

JF - Chemical Communications

IS - 7

ER -

Activity-based high-throughput profiling of metalloprotease inhibitors using small molecule microarrays

Abstract

ASJC Scopus subject areas

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