Activation of cAMP-protein kinase A abrogates STAT5-mediated inhibition of glucocorticoid receptor signaling by interferon-alpha

Keyphrases

• Interferon-α (IFN-α) 100%
• Protein Kinase 100%
• Glucocorticoid Receptor 100%
• Glucocorticoid Signaling 100%
• Receptor Function 50%
• Forskolin 37%
• Inhibitory Effect 37%
• Protein Kinase A Activity 37%
• Inflammatory Pathways 25%
• HT22 Cells 25%
• Protein Kinase A Pathway 25%
• Small Interfering RNA (siRNA) 12%
• Inflammation 12%
• Receptor Activity 12%
• Protein-protein Interaction 12%
• Catalytic Subunit 12%
• Luciferase Activity 12%
• Major Depressive Disorder 12%
• Induced Activation 12%
• Depressed Patients 12%
• Pathway Activation 12%
• Subunit Isoform 12%
• α-effect 12%
• Glucocorticoid Resistance 12%
• Patients with Depression 12%
• Cytokine Effects 12%
• Inhibitory Proteins 12%
• Janus Kinase-signal Transducer 12%
• Hippocampal HT22 Cells 12%

Neuroscience

• Cyclic Adenosine Monophosphate 100%
• Glucocorticoid Receptor 100%
• Protein Kinase A 100%
• Interferon Alfa 100%
• STAT5 100%
• Forskolin 30%
• Dexamethasone 30%
• H-89 20%
• Small Interfering RNA 10%
• Agonist 10%
• Protein-Protein Interaction 10%
• Cell Signaling 10%
• Major Depressive Disorder 10%
• Glucocorticoid 10%
• Enzyme Active Site 10%
• Janus Kinase 10%
• Luciferase 10%

Pharmacology, Toxicology and Pharmaceutical Science

• Cyclic AMP Dependent Protein Kinase 100%
• Glucocorticoid Receptor 100%
• Alpha Interferon 100%
• Forskolin 30%
• Dexamethasone 30%
• H-89 20%
• Cytokine 10%
• Inflammation 10%
• Mouse Mammary Tumor Virus 10%
• Glucocorticoid 10%
• Luciferase 10%
• Small Interfering RNA 10%
• Major Depression 10%
• Janus Kinase 10%
• Cyclic AMP Dependent Protein Kinase Inhibitor 10%