Acridone alkaloids and coumarins from Pleiospermium alatum

B. M.Ratnayake Bandara; A. A.Leslie Gunatilaka; E. M.Kithsiri Wijeratne; John K. MacLeod

doi:10.1016/0031-9422(90)89054-D

Acridone alkaloids and coumarins from Pleiospermium alatum

B. M.Ratnayake Bandara
, A. A.Leslie Gunatilaka
, E. M.Kithsiri Wijeratne
, John K. MacLeod

Research output: Contribution to journal › Article › peer-review

32 Scopus citations

Abstract

The root bark of Pleiospermium alatum afforded five alkaloids, five coumarins, lupeol and stigmasterol. One of the acridones, 1,5,6-trihydroxy-2,3-dimethoxy-10-methyl-9-acridone is a new compound while another, 1-hydroxy-2,3,5,6-tetramethoxy-10-methyl-9-acridone, is a new natural product. Chemotaxonomic aspects of the occurrence of acridone and coumarins in Pleiospermium is discussed. Seselin, one of the coumarins encountered displayed significant antifungal activity against Cladosporium cladosporioides.

Original language	English (US)
Pages (from-to)	297-301
Number of pages	5
Journal	Phytochemistry
Volume	29
Issue number	1
DOIs	https://doi.org/10.1016/0031-9422(90)89054-D
State	Published - 1990
Externally published	Yes

Keywords

Pleiospermium alatum
Rutaceae
acridone alkaloids
antifungal activity.
chemotaxonomy
coumarins
lupeol
stigmasterol

ASJC Scopus subject areas

Biochemistry
Molecular Biology
Plant Science
Horticulture

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10.1016/0031-9422(90)89054-D

Cite this

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title = "Acridone alkaloids and coumarins from Pleiospermium alatum",

abstract = "The root bark of Pleiospermium alatum afforded five alkaloids, five coumarins, lupeol and stigmasterol. One of the acridones, 1,5,6-trihydroxy-2,3-dimethoxy-10-methyl-9-acridone is a new compound while another, 1-hydroxy-2,3,5,6-tetramethoxy-10-methyl-9-acridone, is a new natural product. Chemotaxonomic aspects of the occurrence of acridone and coumarins in Pleiospermium is discussed. Seselin, one of the coumarins encountered displayed significant antifungal activity against Cladosporium cladosporioides.",

keywords = "Pleiospermium alatum, Rutaceae, acridone alkaloids, antifungal activity., chemotaxonomy, coumarins, lupeol, stigmasterol",

author = "Bandara, \{B. M.Ratnayake\} and Gunatilaka, \{A. A.Leslie\} and Wijeratne, \{E. M.Kithsiri\} and MacLeod, \{John K.\}",

year = "1990",

doi = "10.1016/0031-9422(90)89054-D",

language = "English (US)",

volume = "29",

pages = "297--301",

journal = "Phytochemistry",

issn = "0031-9422",

publisher = "Elsevier Ltd",

number = "1",

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T1 - Acridone alkaloids and coumarins from Pleiospermium alatum

AU - Bandara, B. M.Ratnayake

AU - Gunatilaka, A. A.Leslie

AU - Wijeratne, E. M.Kithsiri

AU - MacLeod, John K.

PY - 1990

Y1 - 1990

N2 - The root bark of Pleiospermium alatum afforded five alkaloids, five coumarins, lupeol and stigmasterol. One of the acridones, 1,5,6-trihydroxy-2,3-dimethoxy-10-methyl-9-acridone is a new compound while another, 1-hydroxy-2,3,5,6-tetramethoxy-10-methyl-9-acridone, is a new natural product. Chemotaxonomic aspects of the occurrence of acridone and coumarins in Pleiospermium is discussed. Seselin, one of the coumarins encountered displayed significant antifungal activity against Cladosporium cladosporioides.

AB - The root bark of Pleiospermium alatum afforded five alkaloids, five coumarins, lupeol and stigmasterol. One of the acridones, 1,5,6-trihydroxy-2,3-dimethoxy-10-methyl-9-acridone is a new compound while another, 1-hydroxy-2,3,5,6-tetramethoxy-10-methyl-9-acridone, is a new natural product. Chemotaxonomic aspects of the occurrence of acridone and coumarins in Pleiospermium is discussed. Seselin, one of the coumarins encountered displayed significant antifungal activity against Cladosporium cladosporioides.

KW - Pleiospermium alatum

KW - Rutaceae

KW - acridone alkaloids

KW - antifungal activity.

KW - chemotaxonomy

KW - coumarins

KW - lupeol

KW - stigmasterol

UR - https://www.scopus.com/pages/publications/0000813597

UR - https://www.scopus.com/pages/publications/0000813597#tab=citedBy

U2 - 10.1016/0031-9422(90)89054-D

DO - 10.1016/0031-9422(90)89054-D

M3 - Article

AN - SCOPUS:0000813597

SN - 0031-9422

VL - 29

SP - 297

EP - 301

JO - Phytochemistry

JF - Phytochemistry

IS - 1

ER -

Acridone alkaloids and coumarins from Pleiospermium alatum

Abstract

Keywords

ASJC Scopus subject areas

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