TY - GEN
T1 - Acoustoelectric imaging of time-varying current produced by a clinical deep brain stimulator
AU - Preston, Chet
AU - Qin, Yexian
AU - Burton, Alex
AU - Ingram, Pier
AU - Kasoff, Willard
AU - Witte, Russell
N1 - Publisher Copyright:
© 2017 IEEE.
PY - 2017/10/31
Y1 - 2017/10/31
N2 - Deep brain stimulation (DBS) is an effective therapy for dyskinesia associated with treatments for Parkinson's disease (PD). While current surgical placement of a DBS implant depends on stereotactic coordinates with computed tomography and magnetic resonance imaging for precise localization of the electrode sites, the actual current densities produced by the DBS are not directly observed. This study proposes a novel ultrasound (US) method to visualize these current distributions produced by a DBS via acoustoelectric (AE) imaging. AE imaging uses a focused US beam to locally modulate tissue resistivity due to the AE effect, producing a detectable oscillating voltage from a current flow. The primary goal for this study is to assess baseline performance of AE technology for detecting and resolving current densities near a DBS implant using clinically-relevant stimulation parameters.
AB - Deep brain stimulation (DBS) is an effective therapy for dyskinesia associated with treatments for Parkinson's disease (PD). While current surgical placement of a DBS implant depends on stereotactic coordinates with computed tomography and magnetic resonance imaging for precise localization of the electrode sites, the actual current densities produced by the DBS are not directly observed. This study proposes a novel ultrasound (US) method to visualize these current distributions produced by a DBS via acoustoelectric (AE) imaging. AE imaging uses a focused US beam to locally modulate tissue resistivity due to the AE effect, producing a detectable oscillating voltage from a current flow. The primary goal for this study is to assess baseline performance of AE technology for detecting and resolving current densities near a DBS implant using clinically-relevant stimulation parameters.
UR - http://www.scopus.com/inward/record.url?scp=85039450684&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85039450684&partnerID=8YFLogxK
U2 - 10.1109/ULTSYM.2017.8092105
DO - 10.1109/ULTSYM.2017.8092105
M3 - Conference contribution
AN - SCOPUS:85039450684
T3 - IEEE International Ultrasonics Symposium, IUS
BT - 2017 IEEE International Ultrasonics Symposium, IUS 2017
PB - IEEE Computer Society
T2 - 2017 IEEE International Ultrasonics Symposium, IUS 2017
Y2 - 6 September 2017 through 9 September 2017
ER -