Achieving Long-Term Optimal Outcomes in Geriatric Depression and Anxiety

Benoit H. Mulsant, Ellen Whyte, Eric J. Lenze, Francis Lotrich, Jordan F. Karp, Bruce G. Pollock, Charles F. Reynolds

Research output: Contribution to journalReview articlepeer-review

15 Scopus citations


Depression and anxiety disorders are very common in the elderly. Data accumulated over the past 2 decades have shown that most older patients can tolerate and respond to acute treatment with serotonergic antidepressants, other psychotropic agents, or manual-based psychotherapy. However, outcomes under usual-care conditions remain poor. This review proposes that clinicians may significantly improve the long-term outcomes of their older patients with depression and anxiety by focusing on four key factors: (1) identification and treatment of comorbid conditions; (2) full remission of acute symptoms; (3) education of patients, families, and professional colleagues about the need for long-term treatment; and (4) prevention and management of medication side-effects.

Original languageEnglish (US)
Pages (from-to)27-34
Number of pages8
JournalCNS Spectrums
Issue number12 SUPPL. 3
StatePublished - Dec 2003
Externally publishedYes

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health

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