Acetaminophen-Induced Hepatic Necrosis and Renal Failure

Thomas D. Boyer, Steven L. Rouff

Research output: Contribution to journalArticlepeer-review

175 Scopus citations


A 29-year-old woman ingested 18 gm of acetaminophen with resultant hepatic necrosis and acute renal failure. Since 1966, eighty-six cases of hepatic necrosis secondary to acetaminophen overdose have been described. Acetaminophen overdosage should be considered as one of the causes of acute hepatorenal failure.

Original languageEnglish (US)
Pages (from-to)440-441
Number of pages2
JournalJAMA: The Journal of the American Medical Association
Issue number3
StatePublished - Oct 18 1971
Externally publishedYes

ASJC Scopus subject areas

  • General Medicine


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