TY - GEN
T1 - A system calibration and fast iterative reconstruction method for next-generation SPECT imagers
AU - Miller, Brian W.
AU - Van Holen, Roel
AU - Barrett, Harrison H.
AU - Furenlid, Lars R.
PY - 2011
Y1 - 2011
N2 - Recently, high-resolution gamma cameras have been developed with detectors containing > 105-106 elements. SPECT imagers based on these detectors usually also have a large number of voxel bins and therefore face memory storage issues for the system matrix when performing fast tomographic reconstructions using iterative algorithms. To address these issues, we have developed a method that parameterizes the detector response to a point source and generates the system matrix on the fly during MLEM or OSEM on graphics hardware. The calibration method, interpolation of coefficient data, and reconstruction results are presented in the context of a recently commissioned small-animal SPECT imager, called FastSPECT III.
AB - Recently, high-resolution gamma cameras have been developed with detectors containing > 105-106 elements. SPECT imagers based on these detectors usually also have a large number of voxel bins and therefore face memory storage issues for the system matrix when performing fast tomographic reconstructions using iterative algorithms. To address these issues, we have developed a method that parameterizes the detector response to a point source and generates the system matrix on the fly during MLEM or OSEM on graphics hardware. The calibration method, interpolation of coefficient data, and reconstruction results are presented in the context of a recently commissioned small-animal SPECT imager, called FastSPECT III.
KW - OSEM
KW - Single-photon emission computed tomography (SPECT)
KW - calibration
KW - graphics processing units
KW - high-performance computing
KW - image reconstruction
KW - system matrix
UR - http://www.scopus.com/inward/record.url?scp=84858690992&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84858690992&partnerID=8YFLogxK
U2 - 10.1109/NSSMIC.2011.6153666
DO - 10.1109/NSSMIC.2011.6153666
M3 - Conference contribution
AN - SCOPUS:84858690992
SN - 9781467301183
T3 - IEEE Nuclear Science Symposium Conference Record
SP - 3548
EP - 3553
BT - 2011 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2011
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 2011 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2011
Y2 - 23 October 2011 through 29 October 2011
ER -