Abstract
Synchrotron radiation was used to study the structure of the title compound, C20H19BrN2O3·C 3H7NO, which was obtained as fine fragile needle-shaped crystals by recrystallization from dimethyl-formamide (DMF), one mol-ecule of which is incorporated per asymmetric unit into the crystal. The compound adopts a compact closed conformation with the orientation of the benzyl group such that the aryl ring is positioned over the piperazinedione ring, resulting in a Cspiro⋯Ctrans-C-CPh pseudo-torsion angle of-3.3 (3)°. The five-membered ring is present in an expected envelope conformation and the six-membered piperazinedione ring adopts a less puckered boat-like conformation. Reciprocal amide-to-amide hydrogen bonding between adjacent piperazinedione rings and C-H⋯O inter-actions involving DMF mol-ecules propagate in the crystal as a thick ribbon in the a-axis direction.
Original language | English (US) |
---|---|
Pages (from-to) | o302-o304 |
Journal | Acta Crystallographica Section C: Crystal Structure Communications |
Volume | 66 |
Issue number | 6 |
DOIs | |
State | Published - 2010 |
ASJC Scopus subject areas
- General Biochemistry, Genetics and Molecular Biology
Fingerprint
Dive into the research topics of 'A synchrotron study of (2R,5′S)-5′-benzyl-5-bromo-6-methoxy- spiro-[indane-2,2′-piperazine]-3′,6′-dione dimethyl-formamide solvate'. Together they form a unique fingerprint.Datasets
-
CCDC 782540: Experimental Crystal Structure Determination
Nichol, G. S. (Creator), Murigi, F. N. (Creator) & Mash, E. A. (Creator), Cambridge Crystallographic Data Centre, 2010
DOI: 10.5517/ccv897m, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccv897m&sid=DataCite
Dataset