@article{022e677babcf4124b19d122e5103e9da,
title = "A sternal accelerometer does not impair hemodynamics during piglet CPR",
abstract = "Aim: To determine whether the residual weight of a 260. g sternal accelerometer/force feedback device (AFFD) adversely affects hemodynamics during cardiopulmonary resuscitation in a piglet model of ventricular fibrillation cardiac arrest. Methods: After induction of ventricular fibrillation, cardiopulmonary resuscitation was provided to ten piglets (10.8 ± 1.9. kg) for 12. min while maintaining aortic systolic pressure of 80-90. mmHg during four 3-min periods with or without an AFFD on the chest. Cardiac output and left ventricular myocardial blood flow were determined by neutron-microsphere technique. Results: Using a linear mixed-effect model with residual maximum likelihood estimation to control for changes in cardiopulmonary resuscitation hemodynamics over time, cardiac output and myocardial blood flow did not differ with AFFD versus without AFFD. During the first 6. min, mean (±SEM) cardiac outputs were 0.42 (±0.05). L/min with AFFD versus 0.31 (±0.04). L/min without AFFD, and median left ventricular myocardial blood flows were 40.5 (±7.3). mL/min/100. g with AFFD versus 40.4 (±5.0). mL/min/100. g without AFFD. The mean right atrial diastolic pressures and coronary perfusion pressures were also not different (8 ± 0.7. mmHg versus 8 ± 0.9. mmHg and 16 ± 2. mmHg versus 16 ± 2. mmHg, respectively, during the first 6. min of CPR). Conclusion: The use of a 260. g accelerometer/force feedback device designed for real-time feedback to the rescuer during resuscitation efforts did not adversely affect cardiac output or left ventricular myocardial blood flow during 12. min of chest compressions in a piglet model of ventricular fibrillation cardiac arrest.",
keywords = "CPR, CPR quality, Cardiac arrest, Chest compressions, Leaning, Pediatric, Swine",
author = "Mathias Zuercher and Hilwig, {Ronald W.} and Mike Gura and Jon Nysaether and Nadkarni, {Vinay M.} and Berg, {Marc D.} and Kern, {Karl B.} and Berg, {Robert A.}",
note = "Funding Information: This investigation was funded by a grant from Laerdal Corporation to R.A. Berg. J. Nysaether was an employee of Laerdal Corporation at the time of the investigation and was involved in providing the sternal accelerometer/force feedback device and teaching our laboratory group how to use the device and acquire data with it. He also reviewed the final manuscript (which was written by MZ and RAB) for important intellectual content and final approval. V.M. Nadkarni has unrestricted research grants from Laerdal Foundation for Acute Care Medicine, NIH, NHTSA, AHRQ. K.B. Kern had unrestricted research grants from the Laerdal Foundation for Acute Care Medicine. M. Zuercher, R. Hilwig, M. Gura, and M.D. Berg have nothing to disclose. Funding Information: M. Zuercher has significant support by the “Anaesthesieverein” of the Department of Anesthesia and Intensive Care Medicine, University Hospital Basel, Switzerland. V.M. Nadkarni has unrestricted research grants from the Laerdal Foundation for Acute Care Medicine , NIH , NHTSA , AHRQ . K.B. Kern has grants from the Laerdal Foundation of Stavanger, Norway , and is on the Scientific Advisory committee of Zoll Inc., Chelmsford, MA and PhysioControl Inc., Redmond, WA ; both are not significant. At the time of this investigation, R.A. Berg had an unrestricted grant from the Laerdal Foundation of Stavanger, Norway, and had grants from the National Institutes of Health, National Heart, Lung, and Blood Institute, Bethesda, MD , and from Medtronics Inc., Minneapolis, MN ; all grants were significant. R.A. Berg has not had any industry or foundation grants for >2 years, but has grant support from the National Institutes of Health, Bethesda, MD . ",
year = "2011",
month = sep,
doi = "10.1016/j.resuscitation.2011.04.015",
language = "English (US)",
volume = "82",
pages = "1231--1234",
journal = "Resuscitation",
issn = "0300-9572",
publisher = "Elsevier Ireland Ltd",
number = "9",
}