A SLO topographic imaging approach combined with microperimetry in chorioretinal disorders

Purpose. Scanning Laser Ophthalmoscopy and tomography have been developed as a method for ophthalmic diagnostics over the past decade. However, the application of such imaging technique for diagnosis of chorioreiinal disorders has been limited due to the imaging quality and the lack of knowledge lo interpret the images. In order to better understand the imaging findings, we have optimized the topographic imaging technique and combined it with micro périme try. Methods. Fifty patients (80 eyes) with various chorioretinal disorders diagnosed by clinical examinai ion and angiography were studied using a Rodenstock Scanning Laser Ophthalmoscope (SLO). Confocal and indirect modes were used to acquire topographic images wilh wavelengths of 633nm (HeNe) and 780nm (IR), respectively. The pathologies were assessed along with visual sensitivity. Results .The imaging with HeNe usually provides better contrast and visibility than IR for retinal and especially, subretinal features. Topographic imaging combined with microperimetry is helpful for distinguishing pathologies. Some findings showed a high incidence of visual sensitivity changes, e.g. CNV, fibrovascular scar formation, while some were seldom accompanied by deteciable visual sensilivity changes, e.g. drusen. Follow-up examination indicated that pathological findings usually show up earlier than detectable visual sensitivity change. Conclusions. The topographic imaging combined with microperimetry is a valuable approach for early and differential diagnosis, and for monitoring the course of chorioretinal disorders. Supported in part by a NIH/NEI James A. Shannon Director's Award and Ihe Eye Foundation of Kansas City.