A Single Transcription Factor Drives Toxoplasma gondii Differentiation

Joshua A. Kochanowsky; Anita A. Koshy

doi:10.1016/j.cell.2019.12.038

A Single Transcription Factor Drives Toxoplasma gondii Differentiation

Joshua A. Kochanowsky
, Anita A. Koshy

Research output: Contribution to journal › Comment/debate › peer-review

1 Scopus citations

Abstract

Microbes that cause persistent infections (e.g., herpes viruses) do so by switching from fast-growing lytic states to slow-growing latent states. Waldman et al. have identified a single transcription factor that governs the switch between the lytic and latent forms of Toxoplasma gondii, a parasite that causes a persistent brain infection.

Original language	English (US)
Pages (from-to)	216-218
Number of pages	3
Journal	Cell
Volume	180
Issue number	2
DOIs	https://doi.org/10.1016/j.cell.2019.12.038
State	Published - Jan 23 2020

ASJC Scopus subject areas

General Biochemistry, Genetics and Molecular Biology

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10.1016/j.cell.2019.12.038

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title = "A Single Transcription Factor Drives Toxoplasma gondii Differentiation",

abstract = "Microbes that cause persistent infections (e.g., herpes viruses) do so by switching from fast-growing lytic states to slow-growing latent states. Waldman et al. have identified a single transcription factor that governs the switch between the lytic and latent forms of Toxoplasma gondii, a parasite that causes a persistent brain infection.",

author = "Kochanowsky, \{Joshua A.\} and Koshy, \{Anita A.\}",

note = "Publisher Copyright: {\textcopyright} 2019 Elsevier Inc.",

year = "2020",

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doi = "10.1016/j.cell.2019.12.038",

language = "English (US)",

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T1 - A Single Transcription Factor Drives Toxoplasma gondii Differentiation

AU - Kochanowsky, Joshua A.

AU - Koshy, Anita A.

PY - 2020/1/23

Y1 - 2020/1/23

N2 - Microbes that cause persistent infections (e.g., herpes viruses) do so by switching from fast-growing lytic states to slow-growing latent states. Waldman et al. have identified a single transcription factor that governs the switch between the lytic and latent forms of Toxoplasma gondii, a parasite that causes a persistent brain infection.

AB - Microbes that cause persistent infections (e.g., herpes viruses) do so by switching from fast-growing lytic states to slow-growing latent states. Waldman et al. have identified a single transcription factor that governs the switch between the lytic and latent forms of Toxoplasma gondii, a parasite that causes a persistent brain infection.

UR - https://www.scopus.com/pages/publications/85077924381

UR - https://www.scopus.com/pages/publications/85077924381#tab=citedBy

U2 - 10.1016/j.cell.2019.12.038

DO - 10.1016/j.cell.2019.12.038

M3 - Comment/debate

C2 - 31978340

AN - SCOPUS:85077924381

SN - 0092-8674

VL - 180

SP - 216

EP - 218

JO - Cell

JF - Cell

IS - 2

ER -

A Single Transcription Factor Drives Toxoplasma gondii Differentiation

Abstract

ASJC Scopus subject areas

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