A simple two-photon turn-on fluorescent probe for the selective detection of cysteine based on a dual PeT/ICT mechanism

Xiani Chen; Hang Xu; Shengnan Ma; Hongjuan Tong; Kaiyan Lou; Wei Wang

doi:10.1039/c8ra02138d

A simple two-photon turn-on fluorescent probe for the selective detection of cysteine based on a dual PeT/ICT mechanism

Xiani Chen, Hang Xu, Shengnan Ma, Hongjuan Tong, Kaiyan Lou, Wei Wang

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

Herein, a simple two-photon turn-on fluorescent probe, N-(6-acyl-2-naphthayl)-maleimide (1), based on a dual PeT/ICT quenching mechanism is reported for the highly sensitive and selective detection of cysteine (Cys) over other biothiols. The probe was applied in the two-photon imaging of Cys in cultured HeLa cells, excited by a near-infrared laser at 690 nm.

Original language	English (US)
Pages (from-to)	13388-13392
Number of pages	5
Journal	RSC Advances
Volume	8
Issue number	24
DOIs	https://doi.org/10.1039/c8ra02138d
State	Published - 2018
Externally published	Yes

ASJC Scopus subject areas

General Chemistry
General Chemical Engineering

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title = "A simple two-photon turn-on fluorescent probe for the selective detection of cysteine based on a dual PeT/ICT mechanism",

abstract = "Herein, a simple two-photon turn-on fluorescent probe, N-(6-acyl-2-naphthayl)-maleimide (1), based on a dual PeT/ICT quenching mechanism is reported for the highly sensitive and selective detection of cysteine (Cys) over other biothiols. The probe was applied in the two-photon imaging of Cys in cultured HeLa cells, excited by a near-infrared laser at 690 nm.",

author = "Xiani Chen and Hang Xu and Shengnan Ma and Hongjuan Tong and Kaiyan Lou and Wei Wang",

note = "Funding Information: This work was supported by the National Natural Science Foundation of China (Grant No. 21577037, K. L.) and the East China University of Science and Technology (start-up funds, W. W.). Publisher Copyright: {\textcopyright} 2018 The Royal Society of Chemistry.",

year = "2018",

doi = "10.1039/c8ra02138d",

language = "English (US)",

volume = "8",

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journal = "RSC Advances",

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TY - JOUR

T1 - A simple two-photon turn-on fluorescent probe for the selective detection of cysteine based on a dual PeT/ICT mechanism

AU - Chen, Xiani

AU - Xu, Hang

AU - Ma, Shengnan

AU - Tong, Hongjuan

AU - Lou, Kaiyan

AU - Wang, Wei

N1 - Funding Information: This work was supported by the National Natural Science Foundation of China (Grant No. 21577037, K. L.) and the East China University of Science and Technology (start-up funds, W. W.). Publisher Copyright: © 2018 The Royal Society of Chemistry.

PY - 2018

Y1 - 2018

N2 - Herein, a simple two-photon turn-on fluorescent probe, N-(6-acyl-2-naphthayl)-maleimide (1), based on a dual PeT/ICT quenching mechanism is reported for the highly sensitive and selective detection of cysteine (Cys) over other biothiols. The probe was applied in the two-photon imaging of Cys in cultured HeLa cells, excited by a near-infrared laser at 690 nm.

AB - Herein, a simple two-photon turn-on fluorescent probe, N-(6-acyl-2-naphthayl)-maleimide (1), based on a dual PeT/ICT quenching mechanism is reported for the highly sensitive and selective detection of cysteine (Cys) over other biothiols. The probe was applied in the two-photon imaging of Cys in cultured HeLa cells, excited by a near-infrared laser at 690 nm.

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EP - 13392

JO - RSC Advances

JF - RSC Advances

IS - 24

ER -

A simple two-photon turn-on fluorescent probe for the selective detection of cysteine based on a dual PeT/ICT mechanism

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