A simple synthesis of phosphonoformamides

Colin G. Ferguson; Gregory R.J. Thatcher

doi:10.1055/s-1998-1975

A simple synthesis of phosphonoformamides

Colin G. Ferguson
, Gregory R.J. Thatcher

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

A novel route to C-amides of the antiviral drug Foscarnet via the PFA diester 4 is described. The reaction with amines is facilitated by in situ intramolecular cyclization to form a more reactive intermediate.

Original language	English (US)
Pages (from-to)	1325-1326
Number of pages	2
Journal	Synlett
Issue number	12
DOIs	https://doi.org/10.1055/s-1998-1975
State	Published - Dec 1998
Externally published	Yes

ASJC Scopus subject areas

Organic Chemistry

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10.1055/s-1998-1975

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title = "A simple synthesis of phosphonoformamides",

abstract = "A novel route to C-amides of the antiviral drug Foscarnet via the PFA diester 4 is described. The reaction with amines is facilitated by in situ intramolecular cyclization to form a more reactive intermediate.",

author = "Ferguson, \{Colin G.\} and Thatcher, \{Gregory R.J.\}",

year = "1998",

month = dec,

doi = "10.1055/s-1998-1975",

language = "English (US)",

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journal = "Synlett",

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AU - Thatcher, Gregory R.J.

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SP - 1325

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JO - Synlett

JF - Synlett

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ER -

A simple synthesis of phosphonoformamides

Abstract

ASJC Scopus subject areas

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