A simple synthesis of phosphonoformamides

Colin G. Ferguson, Gregory R.J. Thatcher

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

A novel route to C-amides of the antiviral drug Foscarnet via the PFA diester 4 is described. The reaction with amines is facilitated by in situ intramolecular cyclization to form a more reactive intermediate.

Original languageEnglish (US)
Pages (from-to)1325-1326
Number of pages2
JournalSynlett
Issue number12
DOIs
StatePublished - Dec 1998
Externally publishedYes

ASJC Scopus subject areas

  • Organic Chemistry

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