Abstract
After photo-crosslinking and proteolysis of a photoaffinity labeled ligand to its receptor, the ester group incorporated in the ligand is cleaved by an amine with specific functionality, which displaces the bulk of the ligand from the peptide fragments, and facilitates subsequent tandem mass spectrometric sequencing.
Original language | English (US) |
---|---|
Pages (from-to) | 365-366 |
Number of pages | 2 |
Journal | Chemical Communications |
Issue number | 4 |
DOIs | |
State | Published - Feb 21 1999 |
Externally published | Yes |
ASJC Scopus subject areas
- Catalysis
- Electronic, Optical and Magnetic Materials
- Ceramics and Composites
- General Chemistry
- Surfaces, Coatings and Films
- Metals and Alloys
- Materials Chemistry