A scalable rhodium-catalyzed intermolecular aziridination reaction

David T. Smith; Jon T. Njardarson

doi:10.1002/anie.201400502

A scalable rhodium-catalyzed intermolecular aziridination reaction

David T. Smith, Jon T. Njardarson

Research output: Contribution to journal › Article › peer-review

12 Scopus citations

Abstract

The amine has landed! By employing the rhodium catalyst [Rh ₂(esp)₂] in the presence of a readily available amine source (DPH), unactivated and styrene-type olefins can now be stereospecifally transformed, in high yields at room temperature, into valuable NH aziridine products. esp=α,α,α?,α?-tetramethyl-1,3- benzenedipropionic acid.

Original language	English (US)
Pages (from-to)	4278-4280
Number of pages	3
Journal	Angewandte Chemie - International Edition
Volume	53
Issue number	17
DOIs	https://doi.org/10.1002/anie.201400502
State	Published - Apr 22 2014
Externally published	Yes

Keywords

aziridination
aziridines
heterocycles
nitrene
rhodium

ASJC Scopus subject areas

Catalysis
General Chemistry

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10.1002/anie.201400502

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abstract = "The amine has landed! By employing the rhodium catalyst [Rh 2(esp)2] in the presence of a readily available amine source (DPH), unactivated and styrene-type olefins can now be stereospecifally transformed, in high yields at room temperature, into valuable NH aziridine products. esp=α,α,α?,α?-tetramethyl-1,3- benzenedipropionic acid.",

keywords = "aziridination, aziridines, heterocycles, nitrene, rhodium",

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AU - Njardarson, Jon T.

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N2 - The amine has landed! By employing the rhodium catalyst [Rh 2(esp)2] in the presence of a readily available amine source (DPH), unactivated and styrene-type olefins can now be stereospecifally transformed, in high yields at room temperature, into valuable NH aziridine products. esp=α,α,α?,α?-tetramethyl-1,3- benzenedipropionic acid.

AB - The amine has landed! By employing the rhodium catalyst [Rh 2(esp)2] in the presence of a readily available amine source (DPH), unactivated and styrene-type olefins can now be stereospecifally transformed, in high yields at room temperature, into valuable NH aziridine products. esp=α,α,α?,α?-tetramethyl-1,3- benzenedipropionic acid.

KW - aziridination

KW - aziridines

KW - heterocycles

KW - nitrene

KW - rhodium

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ER -

A scalable rhodium-catalyzed intermolecular aziridination reaction

Abstract

Keywords

ASJC Scopus subject areas

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