A reliable method for localizing deep intracranial sources of the EEG

Dennis B. Smith, Robert D. Sidman, Herman Flanigin, John Henke, David Labiner

Research output: Contribution to journalArticlepeer-review

78 Scopus citations


We have demonstrated the reliability of a noninvasive method for successfully localizing the intracranial origin of the EEG. The dipole localization method (DLM) is a computer-assisted, mathematical method based on electrical field theory and is similar to localization methods currently used by electrocardiologists. In 12 patients with intractable epilepsy who were being evaluated for surgery, a known current source was introduced between two adjacent depth electrodes. Using scalp-recorded EEG only, DLM accurately and reliably localized the source to within 2 cm of the known origin in all instances where a discrete source was present. We conclude that DLM is a valid and reliable noninvasive method for localizing the intracranial source of some scalp-recorded EEG potentials, and that in some patients, use of this method may obviate the need for depth electrode implantation.

Original languageEnglish (US)
Pages (from-to)1702-1707
Number of pages6
Issue number12
StatePublished - Dec 1985

ASJC Scopus subject areas

  • Clinical Neurology


Dive into the research topics of 'A reliable method for localizing deep intracranial sources of the EEG'. Together they form a unique fingerprint.

Cite this