TY - JOUR
T1 - A quick aphasia battery for efficient, reliable, and multidimensional assessment of language function
AU - Wilson, Stephen M.
AU - Eriksson, Dana K.
AU - Schneck, Sarah M.
AU - Lucanie, Jillian M.
N1 - Funding Information:
This research was supported in part by the National Institutes of Health (National Institute on Deafness and Other Communication Disorders) under grants R01 DC013270 and R21 DC016080. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. We thank Stefanie Lauderdale and Melodie Yen for assistance with data collection, Miranda Babiak, Alexa Bautista, Temre Brandt, Ashley Chavez, Angelica McCarron, Hannah Payne and Matt Stib for assistance with development of the battery, Fabi Hirsch, Pélagie Beeson, Kindle Rising and Howard Kirshner for facilitating patient recruitment, Michael de Riesthal for clinical supervision, Bruno Rossion and Gilles Pourtois for permitting us to include their picture stimuli, Laura Calverley for drawing the sentence production stimulus pictures, and the many individuals with and without aphasia who we worked with in the course of developing this instrument.
Publisher Copyright:
© 2018 Wilson et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
PY - 2018/2
Y1 - 2018/2
N2 - This paper describes a quick aphasia battery (QAB) that aims to provide a reliable and multidimensional assessment of language function in about a quarter of an hour, bridging the gap between comprehensive batteries that are time-consuming to administer, and rapid screening instruments that provide limited detail regarding individual profiles of deficits. The QAB is made up of eight subtests, each comprising sets of items that probe different language domains, vary in difficulty, and are scored with a graded system to maximize the informativeness of each item. From the eight subtests, eight summary measures are derived, which constitute a multidimensional profile of language function, quantifying strengths and weaknesses across core language domains. The QAB was administered to 28 individuals with acute stroke and aphasia, 25 individuals with acute stroke but no aphasia, 16 individuals with chronic post-stroke aphasia, and 14 healthy controls. The patients with chronic post-stroke aphasia were tested 3 times each and scored independently by 2 raters to establish test-retest and inter-rater reliability. The Western Aphasia Battery (WAB) was also administered to these patients to assess concurrent validity. We found that all QAB summary measures were sensitive to aphasic deficits in the two groups with aphasia. All measures showed good or excellent test-retest reliability (overall summary measure: intraclass correlation coefficient (ICC) = 0.98), and excellent inter-rater reliability (overall summary measure: ICC = 0.99). Sensitivity and specificity for diagnosis of aphasia (relative to clinical impression) were 0.91 and 0.95 respectively. All QAB measures were highly correlated with corresponding WAB measures where available. Individual patients showed distinct profiles of spared and impaired function across different language domains. In sum, the QAB efficiently and reliably characterized individual profiles of language deficits.
AB - This paper describes a quick aphasia battery (QAB) that aims to provide a reliable and multidimensional assessment of language function in about a quarter of an hour, bridging the gap between comprehensive batteries that are time-consuming to administer, and rapid screening instruments that provide limited detail regarding individual profiles of deficits. The QAB is made up of eight subtests, each comprising sets of items that probe different language domains, vary in difficulty, and are scored with a graded system to maximize the informativeness of each item. From the eight subtests, eight summary measures are derived, which constitute a multidimensional profile of language function, quantifying strengths and weaknesses across core language domains. The QAB was administered to 28 individuals with acute stroke and aphasia, 25 individuals with acute stroke but no aphasia, 16 individuals with chronic post-stroke aphasia, and 14 healthy controls. The patients with chronic post-stroke aphasia were tested 3 times each and scored independently by 2 raters to establish test-retest and inter-rater reliability. The Western Aphasia Battery (WAB) was also administered to these patients to assess concurrent validity. We found that all QAB summary measures were sensitive to aphasic deficits in the two groups with aphasia. All measures showed good or excellent test-retest reliability (overall summary measure: intraclass correlation coefficient (ICC) = 0.98), and excellent inter-rater reliability (overall summary measure: ICC = 0.99). Sensitivity and specificity for diagnosis of aphasia (relative to clinical impression) were 0.91 and 0.95 respectively. All QAB measures were highly correlated with corresponding WAB measures where available. Individual patients showed distinct profiles of spared and impaired function across different language domains. In sum, the QAB efficiently and reliably characterized individual profiles of language deficits.
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U2 - 10.1371/journal.pone.0192773
DO - 10.1371/journal.pone.0192773
M3 - Article
C2 - 29425241
AN - SCOPUS:85041910365
SN - 1932-6203
VL - 13
JO - PLoS One
JF - PLoS One
IS - 2
M1 - e0192773
ER -