A novel esterification procedure applied to synthesis of biologically active esters of Foscarnet

Boris I. Gorin; Colin G. Ferguson; Gregory R.J. Thatcher

doi:10.1016/S0040-4039(97)00491-7

A novel esterification procedure applied to synthesis of biologically active esters of Foscarnet

Boris I. Gorin
, Colin G. Ferguson
, Gregory R.J. Thatcher

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

The high reactivity of the phosphonoformate moiety requires development of a novel synthesis for esters of phosphonoformate, which is reported together with preliminary data on the antiviral activity of these esters.

Original language	English (US)
Pages (from-to)	2791-2794
Number of pages	4
Journal	Tetrahedron Letters
Volume	38
Issue number	16
DOIs	https://doi.org/10.1016/S0040-4039(97)00491-7
State	Published - Apr 21 1997
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(97)00491-7

Cite this

@article{1d8b14ae0c4b43c4bb678e24541403df,

title = "A novel esterification procedure applied to synthesis of biologically active esters of Foscarnet",

abstract = "The high reactivity of the phosphonoformate moiety requires development of a novel synthesis for esters of phosphonoformate, which is reported together with preliminary data on the antiviral activity of these esters.",

author = "Gorin, \{Boris I.\} and Ferguson, \{Colin G.\} and Thatcher, \{Gregory R.J.\}",

note = "Funding Information: Acknowledgements The financial support of Astra Arcus (Sweden) and NSERC (Canada) is gratefully acknowledged, in addition to the encouragement of Dr Brian Pring (Astra).",

year = "1997",

month = apr,

day = "21",

doi = "10.1016/S0040-4039(97)00491-7",

language = "English (US)",

volume = "38",

pages = "2791--2794",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier Ltd",

number = "16",

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T1 - A novel esterification procedure applied to synthesis of biologically active esters of Foscarnet

AU - Gorin, Boris I.

AU - Ferguson, Colin G.

AU - Thatcher, Gregory R.J.

N1 - Funding Information: Acknowledgements The financial support of Astra Arcus (Sweden) and NSERC (Canada) is gratefully acknowledged, in addition to the encouragement of Dr Brian Pring (Astra).

PY - 1997/4/21

Y1 - 1997/4/21

N2 - The high reactivity of the phosphonoformate moiety requires development of a novel synthesis for esters of phosphonoformate, which is reported together with preliminary data on the antiviral activity of these esters.

AB - The high reactivity of the phosphonoformate moiety requires development of a novel synthesis for esters of phosphonoformate, which is reported together with preliminary data on the antiviral activity of these esters.

UR - https://www.scopus.com/pages/publications/0030990376

UR - https://www.scopus.com/pages/publications/0030990376#tab=citedBy

U2 - 10.1016/S0040-4039(97)00491-7

DO - 10.1016/S0040-4039(97)00491-7

M3 - Article

AN - SCOPUS:0030990376

SN - 0040-4039

VL - 38

SP - 2791

EP - 2794

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 16

ER -

A novel esterification procedure applied to synthesis of biologically active esters of Foscarnet

Abstract

ASJC Scopus subject areas

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