A novel bifunctional sulfonamide primary amine-catalyzed enantioselective conjugate addition of ketones to nitroolefins

Fei Xue, Shilei Zhang, Wenhu Duan, Wei Wang

Research output: Contribution to journalArticlepeer-review

74 Scopus citations

Abstract

The enantioselective conjugate addition of a variety of ketones to nitroolefins has been developed. The process is efficiently catalyzed by a novel bifunctional sulfonamide primary amine in good yields and with good levels of enantioselectivity.

Original languageEnglish (US)
Pages (from-to)2194-2198
Number of pages5
JournalAdvanced Synthesis and Catalysis
Volume350
Issue number14-15
DOIs
StatePublished - Oct 6 2008
Externally publishedYes

Keywords

  • Conjugate addition
  • Ketones
  • Nitroolefins
  • Organocatalysis
  • Sulfonamide primary amine

ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry

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