Abstract
A new parenteral vehicle was developed for three poorly water soluble anti-cancer drugs using pluronic L64. A ternary cosolvent system containing pluronic L64 (60%), ethanol (30%), and polysorbate 80 (10%) was formulated. All three drugs tested were stable in this vehicle. Methods of administration usually involve a simple dilution of one part formulation with 2 parts water. The water-diluted formulation of the three drugs studies is physically stable for three days prior to crystallization.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 31-33 |
| Number of pages | 3 |
| Journal | Journal of Parenteral Science and Technology |
| Volume | 41 |
| Issue number | 1 |
| State | Published - 1987 |
ASJC Scopus subject areas
- Pharmaceutical Science