A new design for a SPECT small-animal imager

D. W. Wilson, H. H. Barrett, L. R. Furenlid

Research output: Contribution to conferencePaperpeer-review

7 Scopus citations


We demonstrate, using computer models, the feasibility of a new SPECT system for imaging small animals such as mice. This system consists of four modular scintillation cameras, four multiple-pinhole apertures, electronics, and tomographic reconstruction software. All of these constituents have been designed in our laboratory. The cameras are 120mm×120mm with a resolution of approximately 2mm, the apertures can have either single or multiple pinholes, and reconstruction is performed using the OS-EM algorithm. One major advantage of this system is the design flexibility it offers, as the cameras are easy to move and the apertures are simple to modify. We explored a number of possible configurations. One promising configuration had the four camera faces forming four sides of a cube with multiple-pinhole apertures employed to focus the incoming high-energy photons. This system is rotated three times, so that data are collected from a total of sixteen camera angles. It is shown that this hybrid system has some superior properties to single-aperture-type systems. We conclude that this proposed system offers advantages over current imaging systems in terms of flexibility, simplicity, and performance.

Original languageEnglish (US)
Number of pages4
StatePublished - 2001
Event2001 IEEE Nuclear Science Symposium Conference Record - San Diego, CA, United States
Duration: Nov 4 2001Nov 10 2001


Other2001 IEEE Nuclear Science Symposium Conference Record
Country/TerritoryUnited States
CitySan Diego, CA

ASJC Scopus subject areas

  • Radiation
  • Nuclear and High Energy Physics
  • Radiology Nuclear Medicine and imaging


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