A model for optimizing normal tissue complication probability in the spinal cord using a generalized incomplete repair scheme

D. Levin-Plotnik; R. J. Hamilton; A. Niemierko; S. Akselrod

doi:10.1109/IEMBS.2000.900844

A model for optimizing normal tissue complication probability in the spinal cord using a generalized incomplete repair scheme

D. Levin-Plotnik, R. J. Hamilton, A. Niemierko, S. Akselrod

Research output: Contribution to journal › Article › peer-review

Abstract

To determine the dose fraction sizes and interfraction intervals (IFIs) that minimize the Normal Tissue Complication Probability (NTCP) in the spinal cord, for given treatment dose and time, the concept of incomplete repair in the Linear Quadratic (LQ) model is generalized. An exact solution is found for the case when the IFIs are all equal.

Original language	English (US)
Pages (from-to)	706-709
Number of pages	4
Journal	Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Volume	1
DOIs	https://doi.org/10.1109/IEMBS.2000.900844
State	Published - 2000
Externally published	Yes

Keywords

Incomplete repair
Mathematical models
Normal tissue complication probability

ASJC Scopus subject areas

Signal Processing
Biomedical Engineering
Computer Vision and Pattern Recognition
Health Informatics

Access to Document

10.1109/IEMBS.2000.900844

Cite this

A model for optimizing normal tissue complication probability in the spinal cord using a generalized incomplete repair scheme. / Levin-Plotnik, D.; Hamilton, R. J.; Niemierko, A. et al.
In: Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings, Vol. 1, 2000, p. 706-709.

Research output: Contribution to journal › Article › peer-review

@article{36041cc0612e47ad8acf1d83527c22de,

title = "A model for optimizing normal tissue complication probability in the spinal cord using a generalized incomplete repair scheme",

abstract = "To determine the dose fraction sizes and interfraction intervals (IFIs) that minimize the Normal Tissue Complication Probability (NTCP) in the spinal cord, for given treatment dose and time, the concept of incomplete repair in the Linear Quadratic (LQ) model is generalized. An exact solution is found for the case when the IFIs are all equal.",

keywords = "Incomplete repair, Mathematical models, Normal tissue complication probability",

author = "D. Levin-Plotnik and Hamilton, {R. J.} and A. Niemierko and S. Akselrod",

year = "2000",

doi = "10.1109/IEMBS.2000.900844",

language = "English (US)",

volume = "1",

pages = "706--709",

journal = "Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings",

issn = "0589-1019",

publisher = "Institute of Electrical and Electronics Engineers Inc.",

}

TY - JOUR

T1 - A model for optimizing normal tissue complication probability in the spinal cord using a generalized incomplete repair scheme

AU - Levin-Plotnik, D.

AU - Hamilton, R. J.

AU - Niemierko, A.

AU - Akselrod, S.

PY - 2000

Y1 - 2000

N2 - To determine the dose fraction sizes and interfraction intervals (IFIs) that minimize the Normal Tissue Complication Probability (NTCP) in the spinal cord, for given treatment dose and time, the concept of incomplete repair in the Linear Quadratic (LQ) model is generalized. An exact solution is found for the case when the IFIs are all equal.

AB - To determine the dose fraction sizes and interfraction intervals (IFIs) that minimize the Normal Tissue Complication Probability (NTCP) in the spinal cord, for given treatment dose and time, the concept of incomplete repair in the Linear Quadratic (LQ) model is generalized. An exact solution is found for the case when the IFIs are all equal.

KW - Incomplete repair

KW - Mathematical models

KW - Normal tissue complication probability

UR - http://www.scopus.com/inward/record.url?scp=0034444849&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034444849&partnerID=8YFLogxK

U2 - 10.1109/IEMBS.2000.900844

DO - 10.1109/IEMBS.2000.900844

M3 - Article

AN - SCOPUS:0034444849

SN - 0589-1019

VL - 1

SP - 706

EP - 709

JO - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings

JF - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings

ER -

A model for optimizing normal tissue complication probability in the spinal cord using a generalized incomplete repair scheme

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this