A human onc gene homologous to the transforming gene (v-sis) of simian sarcoma virus

Riccardo Dalla Favera; Edward P. Gelmann; Robert C. Gallo; Flossie Wong-staal

doi:10.1038/292031a0

A human onc gene homologous to the transforming gene (v-sis) of simian sarcoma virus

Riccardo Dalla Favera, Edward P. Gelmann, Robert C. Gallo, Flossie Wong-staal

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Abstract

The human genome contains a single and constant locus (c-sis) related to the transforming gene (v-sis) of simian sarcoma virus. The isolation of a recombinant phage containing the entire human c-sis gene has allowed the study of its genomic organization: c-sis extends over a region of ∼12 kilobases (kb) which includes 1.2 kb of v-sis-related sequences interrupted by four intervening sequences.

Original language	English (US)
Pages (from-to)	31-35
Number of pages	5
Journal	Nature
Volume	292
Issue number	5818
DOIs	https://doi.org/10.1038/292031a0
State	Published - 1981
Externally published	Yes

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title = "A human onc gene homologous to the transforming gene (v-sis) of simian sarcoma virus",

abstract = "The human genome contains a single and constant locus (c-sis) related to the transforming gene (v-sis) of simian sarcoma virus. The isolation of a recombinant phage containing the entire human c-sis gene has allowed the study of its genomic organization: c-sis extends over a region of ∼12 kilobases (kb) which includes 1.2 kb of v-sis-related sequences interrupted by four intervening sequences.",

author = "Favera, {Riccardo Dalla} and Gelmann, {Edward P.} and Gallo, {Robert C.} and Flossie Wong-staal",

year = "1981",

doi = "10.1038/292031a0",

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AU - Gallo, Robert C.

AU - Wong-staal, Flossie

PY - 1981

Y1 - 1981

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AB - The human genome contains a single and constant locus (c-sis) related to the transforming gene (v-sis) of simian sarcoma virus. The isolation of a recombinant phage containing the entire human c-sis gene has allowed the study of its genomic organization: c-sis extends over a region of ∼12 kilobases (kb) which includes 1.2 kb of v-sis-related sequences interrupted by four intervening sequences.

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A human onc gene homologous to the transforming gene (v-sis) of simian sarcoma virus

Abstract

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