A human onc gene homologous to the transforming gene (v-sis) of simian sarcoma virus

Riccardo Dalla Favera, Edward P. Gelmann, Robert C. Gallo, Flossie Wong-staal

Research output: Contribution to journalArticlepeer-review

90 Scopus citations

Abstract

The human genome contains a single and constant locus (c-sis) related to the transforming gene (v-sis) of simian sarcoma virus. The isolation of a recombinant phage containing the entire human c-sis gene has allowed the study of its genomic organization: c-sis extends over a region of ∼12 kilobases (kb) which includes 1.2 kb of v-sis-related sequences interrupted by four intervening sequences.

Original languageEnglish (US)
Pages (from-to)31-35
Number of pages5
JournalNature
Volume292
Issue number5818
DOIs
StatePublished - 1981
Externally publishedYes

ASJC Scopus subject areas

  • General

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