A highly selective fluorescent probe for thiophenols

Wei Jiang, Qingquan Fu, Hongyou Fan, Joe Ho, Wei Wang

Research output: Contribution to journalArticlepeer-review

267 Scopus citations


A rapid response to thiophenols is obtained with probe 1 (see scheme), which induces a significant (> 50-fold) fluorescence enhancement as a result of cleavage of the electron-withdrawing moiety, thus generating strongly fluorescent molecule 2. No fluorescence is obtained with aliphatic thiols, including cysteine and glutathione, or other nucleophiles. (Chemical Equation Presented).

Original languageEnglish (US)
Pages (from-to)8445-8448
Number of pages4
JournalAngewandte Chemie - International Edition
Issue number44
StatePublished - 2007
Externally publishedYes


  • Analytical methods
  • Environmental chemistry
  • Fluorescent probes
  • Fluorophores thiophenols

ASJC Scopus subject areas

  • Catalysis
  • General Chemistry


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