Abstract
A rapid response to thiophenols is obtained with probe 1 (see scheme), which induces a significant (> 50-fold) fluorescence enhancement as a result of cleavage of the electron-withdrawing moiety, thus generating strongly fluorescent molecule 2. No fluorescence is obtained with aliphatic thiols, including cysteine and glutathione, or other nucleophiles. (Chemical Equation Presented).
Original language | English (US) |
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Pages (from-to) | 8445-8448 |
Number of pages | 4 |
Journal | Angewandte Chemie - International Edition |
Volume | 46 |
Issue number | 44 |
DOIs | |
State | Published - 2007 |
Externally published | Yes |
Keywords
- Analytical methods
- Environmental chemistry
- Fluorescent probes
- Fluorophores thiophenols
ASJC Scopus subject areas
- Catalysis
- General Chemistry