A high-resolution CdTe imaging detector with multi-pinhole optics for in-vivo molecular imaging

Shin'ichiro Takeda; Miho Katsuragawa; Tadashi Orita; Fumiki Moriyama; Yasuo Arai; Hirotaka Sugawara; Sayuri Oshita; Goro Yabu; Shin Watanabe; Tadayuki Takahashi; Lars R. Furenlid

doi:10.1016/j.nima.2017.10.037

A high-resolution CdTe imaging detector with multi-pinhole optics for in-vivo molecular imaging

Shin'ichiro Takeda, Miho Katsuragawa, Tadashi Orita, Fumiki Moriyama, Yasuo Arai, Hirotaka Sugawara, Sayuri Oshita, Goro Yabu, Shin Watanabe, Tadayuki Takahashi, Lars R. Furenlid

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

High-resolution CdTe semiconductor detectors with both fine position resolution and high energy resolution hold great promise to improve measurement in various hard X-ray and gamma-ray imaging experiments. In the field of in-vivo molecular imaging, where the molecules labeled with radioisotopes are injected into a small animal and their distribution in a body is detected by gamma-ray imaging detectors externally, a large detection area is also required to obtain a number of projections from multiple pinholes. We have developed a prototype imaging system consisting of a 32 mm-wide CdTe double-sided strip detector equipped with multi-pinhole optics. We describe its imaging capability, as studied through experiments with radioisotopes for medical use (¹²⁵I and ¹¹¹In) and a 3D phantom.

Original language	English (US)
Pages (from-to)	57-60
Number of pages	4
Journal	Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
Volume	912
DOIs	https://doi.org/10.1016/j.nima.2017.10.037
State	Published - Dec 21 2018

Keywords

CdTe
Gamma-ray
In-vivo
Molecular imaging
Semiconductor detectors

ASJC Scopus subject areas

Nuclear and High Energy Physics
Instrumentation

Access to Document

10.1016/j.nima.2017.10.037

Cite this

Takeda, S., Katsuragawa, M., Orita, T., Moriyama, F., Arai, Y., Sugawara, H., Oshita, S., Yabu, G., Watanabe, S., Takahashi, T., & Furenlid, L. R. (2018). A high-resolution CdTe imaging detector with multi-pinhole optics for in-vivo molecular imaging. Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 912, 57-60. https://doi.org/10.1016/j.nima.2017.10.037

A high-resolution CdTe imaging detector with multi-pinhole optics for in-vivo molecular imaging. / Takeda, Shin'ichiro; Katsuragawa, Miho; Orita, Tadashi et al.
In: Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, Vol. 912, 21.12.2018, p. 57-60.

Research output: Contribution to journal › Article › peer-review

Takeda, S, Katsuragawa, M, Orita, T, Moriyama, F, Arai, Y, Sugawara, H, Oshita, S, Yabu, G, Watanabe, S, Takahashi, T & Furenlid, LR 2018, 'A high-resolution CdTe imaging detector with multi-pinhole optics for in-vivo molecular imaging', Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, vol. 912, pp. 57-60. https://doi.org/10.1016/j.nima.2017.10.037

@article{690d9a0126fa405682a06631dac83673,

title = "A high-resolution CdTe imaging detector with multi-pinhole optics for in-vivo molecular imaging",

abstract = "High-resolution CdTe semiconductor detectors with both fine position resolution and high energy resolution hold great promise to improve measurement in various hard X-ray and gamma-ray imaging experiments. In the field of in-vivo molecular imaging, where the molecules labeled with radioisotopes are injected into a small animal and their distribution in a body is detected by gamma-ray imaging detectors externally, a large detection area is also required to obtain a number of projections from multiple pinholes. We have developed a prototype imaging system consisting of a 32 mm-wide CdTe double-sided strip detector equipped with multi-pinhole optics. We describe its imaging capability, as studied through experiments with radioisotopes for medical use (125I and 111In) and a 3D phantom.",

keywords = "CdTe, Gamma-ray, In-vivo, Molecular imaging, Semiconductor detectors",

author = "Shin'ichiro Takeda and Miho Katsuragawa and Tadashi Orita and Fumiki Moriyama and Yasuo Arai and Hirotaka Sugawara and Sayuri Oshita and Goro Yabu and Shin Watanabe and Tadayuki Takahashi and Furenlid, {Lars R.}",

note = "Funding Information: This work was supported in part by JSPS KAKENHI grant number 26706024 . L. R. Furenlid was partially supported by NIBIB grant P41-EB002035 , “The Center for Gamma-Ray Imaging”. M. Katsuragawa was supported by a Grant-in-Aid for JSPS Fellows. Publisher Copyright: {\textcopyright} 2017 Elsevier B.V.",

year = "2018",

month = dec,

day = "21",

doi = "10.1016/j.nima.2017.10.037",

language = "English (US)",

volume = "912",

pages = "57--60",

journal = "Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment",

issn = "0168-9002",

publisher = "Elsevier",

}

TY - JOUR

T1 - A high-resolution CdTe imaging detector with multi-pinhole optics for in-vivo molecular imaging

AU - Takeda, Shin'ichiro

AU - Katsuragawa, Miho

AU - Orita, Tadashi

AU - Moriyama, Fumiki

AU - Arai, Yasuo

AU - Sugawara, Hirotaka

AU - Oshita, Sayuri

AU - Yabu, Goro

AU - Watanabe, Shin

AU - Takahashi, Tadayuki

AU - Furenlid, Lars R.

N1 - Funding Information: This work was supported in part by JSPS KAKENHI grant number 26706024 . L. R. Furenlid was partially supported by NIBIB grant P41-EB002035 , “The Center for Gamma-Ray Imaging”. M. Katsuragawa was supported by a Grant-in-Aid for JSPS Fellows. Publisher Copyright: © 2017 Elsevier B.V.

PY - 2018/12/21

Y1 - 2018/12/21

N2 - High-resolution CdTe semiconductor detectors with both fine position resolution and high energy resolution hold great promise to improve measurement in various hard X-ray and gamma-ray imaging experiments. In the field of in-vivo molecular imaging, where the molecules labeled with radioisotopes are injected into a small animal and their distribution in a body is detected by gamma-ray imaging detectors externally, a large detection area is also required to obtain a number of projections from multiple pinholes. We have developed a prototype imaging system consisting of a 32 mm-wide CdTe double-sided strip detector equipped with multi-pinhole optics. We describe its imaging capability, as studied through experiments with radioisotopes for medical use (125I and 111In) and a 3D phantom.

AB - High-resolution CdTe semiconductor detectors with both fine position resolution and high energy resolution hold great promise to improve measurement in various hard X-ray and gamma-ray imaging experiments. In the field of in-vivo molecular imaging, where the molecules labeled with radioisotopes are injected into a small animal and their distribution in a body is detected by gamma-ray imaging detectors externally, a large detection area is also required to obtain a number of projections from multiple pinholes. We have developed a prototype imaging system consisting of a 32 mm-wide CdTe double-sided strip detector equipped with multi-pinhole optics. We describe its imaging capability, as studied through experiments with radioisotopes for medical use (125I and 111In) and a 3D phantom.

KW - CdTe

KW - Gamma-ray

KW - In-vivo

KW - Molecular imaging

KW - Semiconductor detectors

UR - http://www.scopus.com/inward/record.url?scp=85037028850&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85037028850&partnerID=8YFLogxK

U2 - 10.1016/j.nima.2017.10.037

DO - 10.1016/j.nima.2017.10.037

M3 - Article

AN - SCOPUS:85037028850

SN - 0168-9002

VL - 912

SP - 57

EP - 60

JO - Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment

JF - Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment

ER -

A high-resolution CdTe imaging detector with multi-pinhole optics for in-vivo molecular imaging

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this