A DNA-damaging sesquiterpene and other constituents from Frullania nisquallensis

Youn C. Kim; Vanderlan Da S. Bolzani; Nina Baj; A. A.Leslie Gunatilaka; David G.I. Kingston

doi:10.1055/s-2006-957800

A DNA-damaging sesquiterpene and other constituents from Frullania nisquallensis

Youn C. Kim, Vanderlan Da S. Bolzani, Nina Baj, A. A.Leslie Gunatilaka, David G.I. Kingston

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

Bioassay-guided fractionation of an MeCOEt extract of Frullania nisquallensis Sull. has furnished a DNA-damaging sesquiterpene, costunolide (1), and two inactive compounds, a sesquiterpene (-)-frullanolide (2) and a tridepside tenuiorin (3). ¹³C-NMR data of 3 are reported.

Original language	English (US)
Pages (from-to)	61-63
Number of pages	3
Journal	Planta Medica
Volume	62
Issue number	1
DOIs	https://doi.org/10.1055/s-2006-957800
State	Published - 1996

ASJC Scopus subject areas

Analytical Chemistry
Molecular Medicine
Pharmacology
Pharmaceutical Science
Drug Discovery
Complementary and alternative medicine
Organic Chemistry

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title = "A DNA-damaging sesquiterpene and other constituents from Frullania nisquallensis",

abstract = "Bioassay-guided fractionation of an MeCOEt extract of Frullania nisquallensis Sull. has furnished a DNA-damaging sesquiterpene, costunolide (1), and two inactive compounds, a sesquiterpene (-)-frullanolide (2) and a tridepside tenuiorin (3). 13C-NMR data of 3 are reported.",

author = "Kim, {Youn C.} and Bolzani, {Vanderlan Da S.} and Nina Baj and Gunatilaka, {A. A.Leslie} and Kingston, {David G.I.}",

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AU - Kim, Youn C.

AU - Bolzani, Vanderlan Da S.

AU - Baj, Nina

AU - Gunatilaka, A. A.Leslie

AU - Kingston, David G.I.

PY - 1996

Y1 - 1996

N2 - Bioassay-guided fractionation of an MeCOEt extract of Frullania nisquallensis Sull. has furnished a DNA-damaging sesquiterpene, costunolide (1), and two inactive compounds, a sesquiterpene (-)-frullanolide (2) and a tridepside tenuiorin (3). 13C-NMR data of 3 are reported.

AB - Bioassay-guided fractionation of an MeCOEt extract of Frullania nisquallensis Sull. has furnished a DNA-damaging sesquiterpene, costunolide (1), and two inactive compounds, a sesquiterpene (-)-frullanolide (2) and a tridepside tenuiorin (3). 13C-NMR data of 3 are reported.

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JO - Planta Medica

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IS - 1

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A DNA-damaging sesquiterpene and other constituents from Frullania nisquallensis

Abstract

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