A comparative study on the uptake of ascorbic acid by the iris-ciliary body of the rabbit, guinea pig and rat

Nicholas A. Delamere; Richard N. Williams

doi:10.1016/0305-0491(87)90253-7

A comparative study on the uptake of ascorbic acid by the iris-ciliary body of the rabbit, guinea pig and rat

Nicholas A. Delamere
, Richard N. Williams

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

1. 1. The uptake of ¹⁴C-ascorbic acid by the iris-ciliary body in vitro was examined in the rabbit, guinea pig and rat. 2. 2. It was observed that iris-ciliary body from the rabbit and guinea pig, but not the rat, accumulated ¹⁴C-ascorbate to levels exceeding that in the bathing medium. 3. 3. In all three species, the uptake of ¹⁴C-ascorbate was diminished by cold temperature; the degree of uptake at 0°C was similar in the rabbit, guinea pig and rat iris-ciliary body. 4. 4. Chromatographic examination of the ¹⁴C accumulated by the rabbit and guinea pig tissue demonstrated that the label remains almost exclusively as ¹⁴C-ascorbate.

Original language	English (US)
Pages (from-to)	847-849
Number of pages	3
Journal	Comparative Biochemistry and Physiology -- Part B: Biochemistry and
Volume	88
Issue number	3
DOIs	https://doi.org/10.1016/0305-0491(87)90253-7
State	Published - 1987
Externally published	Yes

ASJC Scopus subject areas

Aquatic Science
Animal Science and Zoology
Molecular Biology
Biochemistry
Physiology

Access to Document

10.1016/0305-0491(87)90253-7

Cite this

@article{f9a2b0d425da44e185793a7a6bb83275,

title = "A comparative study on the uptake of ascorbic acid by the iris-ciliary body of the rabbit, guinea pig and rat",

abstract = "1. 1. The uptake of 14C-ascorbic acid by the iris-ciliary body in vitro was examined in the rabbit, guinea pig and rat. 2. 2. It was observed that iris-ciliary body from the rabbit and guinea pig, but not the rat, accumulated 14C-ascorbate to levels exceeding that in the bathing medium. 3. 3. In all three species, the uptake of 14C-ascorbate was diminished by cold temperature; the degree of uptake at 0°C was similar in the rabbit, guinea pig and rat iris-ciliary body. 4. 4. Chromatographic examination of the 14C accumulated by the rabbit and guinea pig tissue demonstrated that the label remains almost exclusively as 14C-ascorbate.",

author = "Delamere, \{Nicholas A.\} and Williams, \{Richard N.\}",

note = "Funding Information: Acknowledgements\textasciitilde{}This study was suppported by United States Public Health Service research grant No. EY05412 from the National Eye Institute.",

year = "1987",

doi = "10.1016/0305-0491(87)90253-7",

language = "English (US)",

volume = "88",

pages = "847--849",

journal = "Comparative Biochemistry and Physiology -- Part B: Biochemistry and",

issn = "0305-0491",

publisher = "Elsevier Inc.",

number = "3",

}

TY - JOUR

T1 - A comparative study on the uptake of ascorbic acid by the iris-ciliary body of the rabbit, guinea pig and rat

AU - Delamere, Nicholas A.

AU - Williams, Richard N.

N1 - Funding Information: Acknowledgements~This study was suppported by United States Public Health Service research grant No. EY05412 from the National Eye Institute.

PY - 1987

Y1 - 1987

N2 - 1. 1. The uptake of 14C-ascorbic acid by the iris-ciliary body in vitro was examined in the rabbit, guinea pig and rat. 2. 2. It was observed that iris-ciliary body from the rabbit and guinea pig, but not the rat, accumulated 14C-ascorbate to levels exceeding that in the bathing medium. 3. 3. In all three species, the uptake of 14C-ascorbate was diminished by cold temperature; the degree of uptake at 0°C was similar in the rabbit, guinea pig and rat iris-ciliary body. 4. 4. Chromatographic examination of the 14C accumulated by the rabbit and guinea pig tissue demonstrated that the label remains almost exclusively as 14C-ascorbate.

AB - 1. 1. The uptake of 14C-ascorbic acid by the iris-ciliary body in vitro was examined in the rabbit, guinea pig and rat. 2. 2. It was observed that iris-ciliary body from the rabbit and guinea pig, but not the rat, accumulated 14C-ascorbate to levels exceeding that in the bathing medium. 3. 3. In all three species, the uptake of 14C-ascorbate was diminished by cold temperature; the degree of uptake at 0°C was similar in the rabbit, guinea pig and rat iris-ciliary body. 4. 4. Chromatographic examination of the 14C accumulated by the rabbit and guinea pig tissue demonstrated that the label remains almost exclusively as 14C-ascorbate.

UR - https://www.scopus.com/pages/publications/0023497573

UR - https://www.scopus.com/pages/publications/0023497573#tab=citedBy

U2 - 10.1016/0305-0491(87)90253-7

DO - 10.1016/0305-0491(87)90253-7

M3 - Article

C2 - 3427921

AN - SCOPUS:0023497573

SN - 0305-0491

VL - 88

SP - 847

EP - 849

JO - Comparative Biochemistry and Physiology -- Part B: Biochemistry and

JF - Comparative Biochemistry and Physiology -- Part B: Biochemistry and

IS - 3

ER -

A comparative study on the uptake of ascorbic acid by the iris-ciliary body of the rabbit, guinea pig and rat

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this