TY - JOUR
T1 - A comparative study on the uptake of ascorbic acid by the iris-ciliary body of the rabbit, guinea pig and rat
AU - Delamere, Nicholas A.
AU - Williams, Richard N.
N1 - Funding Information:
Acknowledgements~This study was suppported by United States Public Health Service research grant No. EY05412 from the National Eye Institute.
PY - 1987
Y1 - 1987
N2 - 1. 1. The uptake of 14C-ascorbic acid by the iris-ciliary body in vitro was examined in the rabbit, guinea pig and rat. 2. 2. It was observed that iris-ciliary body from the rabbit and guinea pig, but not the rat, accumulated 14C-ascorbate to levels exceeding that in the bathing medium. 3. 3. In all three species, the uptake of 14C-ascorbate was diminished by cold temperature; the degree of uptake at 0°C was similar in the rabbit, guinea pig and rat iris-ciliary body. 4. 4. Chromatographic examination of the 14C accumulated by the rabbit and guinea pig tissue demonstrated that the label remains almost exclusively as 14C-ascorbate.
AB - 1. 1. The uptake of 14C-ascorbic acid by the iris-ciliary body in vitro was examined in the rabbit, guinea pig and rat. 2. 2. It was observed that iris-ciliary body from the rabbit and guinea pig, but not the rat, accumulated 14C-ascorbate to levels exceeding that in the bathing medium. 3. 3. In all three species, the uptake of 14C-ascorbate was diminished by cold temperature; the degree of uptake at 0°C was similar in the rabbit, guinea pig and rat iris-ciliary body. 4. 4. Chromatographic examination of the 14C accumulated by the rabbit and guinea pig tissue demonstrated that the label remains almost exclusively as 14C-ascorbate.
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U2 - 10.1016/0305-0491(87)90253-7
DO - 10.1016/0305-0491(87)90253-7
M3 - Article
C2 - 3427921
AN - SCOPUS:0023497573
SN - 0305-0491
VL - 88
SP - 847
EP - 849
JO - Comparative Biochemistry and Physiology -- Part B: Biochemistry and
JF - Comparative Biochemistry and Physiology -- Part B: Biochemistry and
IS - 3
ER -