TY - JOUR
T1 - A coming of age for vascular access research
T2 - the good, the bad, and the ugly!
AU - Celdran Bonafonte, Diego
AU - Roy-Chaudhury, Prabir
N1 - Publisher Copyright:
© 2019 International Society of Nephrology
PY - 2019/6
Y1 - 2019/6
N2 - Dialysis vascular access dysfunction remains an important clinical problem with a very significant morbidity, mortality, and socio-economic cost. Despite the magnitude of the clinical problem, there are currently no truly effective therapies for vascular access dysfunction. Through a high-quality scientific investigation, Liang et al. have identified a number of novel biological pathways responsible for “mouse” arteriovenous fistula stenosis. We hope that the identification of these druggable pathways (targets)will allow for the development of new and effective therapies for vascular access dysfunction, through the creation of an innovation substrate for dialysis vascular access.
AB - Dialysis vascular access dysfunction remains an important clinical problem with a very significant morbidity, mortality, and socio-economic cost. Despite the magnitude of the clinical problem, there are currently no truly effective therapies for vascular access dysfunction. Through a high-quality scientific investigation, Liang et al. have identified a number of novel biological pathways responsible for “mouse” arteriovenous fistula stenosis. We hope that the identification of these druggable pathways (targets)will allow for the development of new and effective therapies for vascular access dysfunction, through the creation of an innovation substrate for dialysis vascular access.
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U2 - 10.1016/j.kint.2019.02.035
DO - 10.1016/j.kint.2019.02.035
M3 - Comment/debate
C2 - 31122705
AN - SCOPUS:85065483615
SN - 0085-2538
VL - 95
SP - 1294
EP - 1295
JO - Kidney International
JF - Kidney International
IS - 6
ER -