Find Scholarly Works

Search results

• Structure-activity relationship of biphalin. The synthesis and biological activities of new analogues with modifications in positions 3 and 4

  Misicka, A., Lipkowski, A. W., Horvath, R., Davis, P., Porreca, F., Yamamura, H. I. & Hruby, V. J., Mar 7 1997, In: Life Sciences. 60, 15, p. 1263-1269 7 p.

  Research output: Contribution to journal › Article › peer-review
  35 Scopus citations

• Structure–Activity Relationships and Transcriptomic Analysis of Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors

  Poloznikov, A. A., Nikulin, S. V., Hushpulian, D. M., Khristichenko, A. Y., Osipyants, A. I., Asachenko, A. F., Shurupova, O. V., Savin, S. S., Lee, S. H., Gaisina, I. N., Thatcher, G. R. J., Narciso, A., Chang, E. P., Kazakov, S. V., Krucher, N., Tishkov, V. I., Thomas, B. & Gazaryan, I. G., Feb 2022, In: Antioxidants. 11, 2, 220.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Structure-activity relationships for a family of benzothiophene selective estrogen receptor modulators including raloxifene and arzoxifene

  Overk, C. R., Peng, K. W., Asghodom, R. T., Kastrati, I., Lantvit, D. D., Qin, Z., Frasor, J., Bolton, J. L. & Thatcher, G. R. J., Oct 8 2007, In: ChemMedChem. 2, 10, p. 1520-1526 7 p.

  Research output: Contribution to journal › Article › peer-review
  35 Scopus citations

• Structure-activity relationships for SNC80 and related compounds at cloned human delta and mu opioid receptors

  Knapp, R. J., Santoro, G., De Leon, I. A., Lee, K. B., Edsall, S. A., Waite, S., Malatynska, E., Varga, E., Calderon, S. N., Rice, K. C., Rothman, R. B., Porreca, F., Roeske, W. R. & Yamamura, H. I., Jun 1996, In: Journal of Pharmacology and Experimental Therapeutics. 277, 3, p. 1284-1291 8 p.

  Research output: Contribution to journal › Article › peer-review
  62 Scopus citations

• Structure-activity relationships for withanolides as inducers of the cellular heat-shock response

  Wijeratne, E. M. K., Xu, Y. M., Scherz-Shouval, R., Marron, M. T., Rocha, D. D., Liu, M. X., Costa-Lotufo, L. V., Santagata, S., Lindquist, S., Whitesell, L. & Gunatilaka, A. A. L., Apr 10 2014, In: Journal of Medicinal Chemistry. 57, 7, p. 2851-2863 13 p.

  Research output: Contribution to journal › Article › peer-review
  46 Scopus citations

• Structure-Activity Relationships of (+)-CC-1065 Analogues in the Inhibition of Helicase-Catalyzed Unwinding of Duplex DNA

  Sun, D. & Hurley, L. H., May 1 1992, In: Journal of Medicinal Chemistry. 35, 10, p. 1773-1782 10 p.

  Research output: Contribution to journal › Article › peer-review
  21 Scopus citations

• Structure-Activity Relationships of [des-Arg⁷]Dynorphin A Analogues at the ΰ Opioid Receptor

  Ramos-Colon, C. N., Lee, Y. S., Remesic, M., Hall, S. M., Lavigne, J., Davis, P., Sandweiss, A. J., McIntosh, M. I., Hanson, J., Largent-Milnes, T. M., Vanderah, T. W., Streicher, J., Porreca, F. & Hruby, V. J., Nov 23 2016, In: Journal of Medicinal Chemistry. 59, 22, p. 10291-10298 8 p.

  Research output: Contribution to journal › Article › peer-review
  10 Scopus citations

• Structure‐Activity Relationships of [Nle⁴, D‐Phe⁷]α‐MSH: Discovery of a Tripeptidyl Agonist Exhibiting Sustained Bioactivity

  SAWYER, TOMI. K., CASTRUCCI, ANA. M., STAPLES, DOUGLAS. J., AFFHOLTER, JOSEPH. A., DE VAUX, ANNE. E., HRUBY, VICTOR. J. & HADLEY, MAC. E., May 1993, In: Annals of the New York Academy of Sciences. 680, 1, p. 597-599 3 p.

  Research output: Contribution to journal › Article › peer-review
  38 Scopus citations

• Structure-activity relationships of analogues of higly potent opioid peptide, biphalin

  Misicka, A., Lipkowski, A. W., Horvath, R., Davis, P., Porreca, F., Yamamura, H. I. & Hruby, V. J., Feb 21 1994, In: Regulatory Peptides. 53, SUPPL. 1, p. S131-S132

  Research output: Contribution to journal › Article › peer-review
  7 Scopus citations

• Structure-activity relationships of a series of [D-Ala²]deltorphin I and II analogues; in vitro blood-brain barrier permeability and stability

  Thomas, S. A., Abbruscato, T. J., Hau, V. S., Gillespie, T. J., Zsigo, J., Hruby, V. J. & Davis, T. P., May 1997, In: Journal of Pharmacology and Experimental Therapeutics. 281, 2, p. 817-825 9 p.

  Research output: Contribution to journal › Article › peer-review
  35 Scopus citations

• Structure-activity relationships of bifunctional cyclic disulfide peptides based on overlapping pharmacophores at opioid and cholecystokinin receptors

  Agnes, R. S., Ying, J., Kövér, K. E., Lee, Y. S., Davis, P., Ma, S. W., Badghisi, H., Porreca, F., Lai, J. & Hruby, V. J., Aug 2008, In: Peptides. 29, 8, p. 1413-1423 11 p.

  Research output: Contribution to journal › Article › peer-review
  19 Scopus citations

• Structure-activity relationships of bifunctional peptides based on overlapping pharmacophores at opioid and cholecystokinin receptors

  Agnes, R. S., Lee, Y. S., Davis, P., Ma, S. W., Badghisi, H., Porreca, F., Lai, J. & Hruby, V. J., May 18 2006, In: Journal of Medicinal Chemistry. 49, 10, p. 2868-2875 8 p.

  Research output: Contribution to journal › Article › peer-review
  40 Scopus citations

• Structure-activity relationships of cyclic lactam analogues of α-melanocyte-stimulating hormone (α-MSH) targeting the human melanocortin-3 receptor

  Mayorov, A. V., Cai, M., Palmer, E. S., Dedek, M. M., Cain, J. P., Van Scoy, A. R., Tan, B., Vagner, J., Trivedi, D. & Hruby, V. J., Jan 24 2008, In: Journal of Medicinal Chemistry. 51, 2, p. 187-195 9 p.

  Research output: Contribution to journal › Article › peer-review
  10 Scopus citations

• Structure-activity relationships of diphenylpiperazine N-type calcium channel inhibitors

  Pajouhesh, H., Feng, Z. P., Ding, Y., Zhang, L., Pajouhesh, H., Morrison, J. L., Belardetti, F., Tringham, E., Simonson, E., Vanderah, T. W., Porreca, F., Zamponi, G. W., Mitscher, L. A. & Snutch, T. P., Feb 15 2010, In: Bioorganic and Medicinal Chemistry Letters. 20, 4, p. 1378-1383 6 p.

  Research output: Contribution to journal › Article › peer-review
  36 Scopus citations

• Structure-activity relationships of non-opioid [des-Arg⁷]-dynorphin A analogues for bradykinin receptors

  Lee, Y. S., Rankin, D., Hall, S. M., Ramos-Colon, C., Ortiz, J. J., Kupp, R., Porreca, F., Lai, J. & Hruby, V. J., Nov 1 2014, In: Bioorganic and Medicinal Chemistry Letters. 24, 21, p. 4976-4979 4 p.

  Research output: Contribution to journal › Article › peer-review
  9 Scopus citations

• Structure-activity relationships of novel cyclic α-MSH/β-MSH hybrid analogues that lead to potent and selective ligands for the human MC3R and human MC5R

  Balse-Srinivasan, P., Grieco, P., Cai, M., Trivedi, D. & Hruby, V. J., Aug 14 2003, In: Journal of Medicinal Chemistry. 46, 17, p. 3728-3733 6 p.

  Research output: Contribution to journal › Article › peer-review
  28 Scopus citations

• Structure-activity relationships of trimethoxybenzyl piperazine N-type calcium channel inhibitors

  Pajouhesh, H., Feng, Z. P., Zhang, L., Pajouhesh, H., Jiang, X., Hendricson, A., Dong, H., Tringham, E., Ding, Y., Vanderah, T. W., Porreca, F., Belardetti, F., Zamponi, G. W., Mitscher, L. A. & Snutch, T. P., Jun 15 2012, In: Bioorganic and Medicinal Chemistry Letters. 22, 12, p. 4153-4158 6 p.

  Research output: Contribution to journal › Article › peer-review
  20 Scopus citations

• Structure-Activity Relationships of Withanolides as Antiproliferative Agents for Multiple Myeloma: Comparison of Activity in 2D Models and a 3D Coculture Model

  Freitas Misakyan, M. F., Wijeratne, E. M. K., Issa, M. E., Xu, Y. M., Monteillier, A., Gunatilaka, A. A. L. & Cuendet, M., Aug 27 2021, In: Journal Of Natural Products. 84, 8, p. 2321-2335 15 p.

  Research output: Contribution to journal › Article › peer-review

• Structure-Activity Relationships of γ-MSH Analogues at the Human Melanocortin MC3, MC4, and MC5 Receptors. Discovery of Highly Selective hMC3R, hMC4R, and hMC5R Analogues

  Balse-Srinivasan, P., Grieco, P., Cai, M., Trivedi, D. & Hruby, V. J., Nov 6 2003, In: Journal of Medicinal Chemistry. 46, 23, p. 4965-4973 9 p.

  Research output: Contribution to journal › Article › peer-review
  24 Scopus citations

• Structure-activity relationship study of growth inhibitory 2-styrylchromones against carcinoma cells

  Lin, C., Lu, P. J., Yang, C. N., Hulme, C. & Shaw, A. Y., May 2013, In: Medicinal Chemistry Research. 22, 5, p. 2385-2394 10 p.

  Research output: Contribution to journal › Article › peer-review
  9 Scopus citations

• Structure-activity relations of the cardiac gap junction channel

  Spray, D. C. & Burt, J. M., 1990, In: American Journal of Physiology - Cell Physiology. 258, 2 27-2, p. C195-C205

  Research output: Contribution to journal › Review article › peer-review
  248 Scopus citations

• Structure-Activity Studies of a Novel Bicyclic Oxytocin Antagonist

  Smith, D. D., Slaninova, J. & Hruby, V. J., May 1 1992, In: Journal of Medicinal Chemistry. 35, 9, p. 1558-1563 6 p.

  Research output: Contribution to journal › Article › peer-review
  39 Scopus citations

• Structure-Activity Studies of Highly Potent Cyclic [formula omitted]Melanotropin Analogues

  Knittel, J. J., Sawyer, T. K., Hruby, V. J. & Hadley, M. E., Feb 1983, In: Journal of Medicinal Chemistry. 26, 2, p. 125-129 5 p.

  Research output: Contribution to journal › Article › peer-review
  42 Scopus citations

• Structure-activity studies of hydrophobic amino acid replacements at positions 9, 11 and 16 of glucagon

  Sturm, N. S., Hutzler, A. M., David, C. S., Azizeh, B. Y., Trivedi, D. & Hruby, V. J., 1997, In: Journal of Peptide Research. 49, 4, p. 293-299 7 p.

  Research output: Contribution to journal › Article › peer-review
  5 Scopus citations

• Structure-activity studies of new melanocortin peptides containing an aromatic amino acid at the N-terminal position

  Grieco, P., Cai, M., Mayorov, A. V., Trivedi, D. & Hruby, V. J., Feb 2006, In: Peptides. 27, 2, p. 472-481 10 p.

  Research output: Contribution to journal › Article › peer-review
  10 Scopus citations

• Structure-activity studies of peptides from the "hot-spot" region of human CD2 protein: Development of peptides for immunomodulation

  Liu, J., Ying, J., Chow, V. T. K., Hruby, V. J. & Satyanarayanajois, S. D., Oct 6 2005, In: Journal of Medicinal Chemistry. 48, 20, p. 6236-6249 14 p.

  Research output: Contribution to journal › Article › peer-review
  9 Scopus citations

• Structure-activity studies of PTPRD phosphatase inhibitors identify a 7-cyclopentymethoxy illudalic acid analog candidate for development

  Henderson, I. M., Zeng, F., Bhuiyan, N. H., Luo, D., Martinez, M., Smoake, J., Bi, F., Perera, C., Johnson, D., Prisinzano, T. E., Wang, W. & Uhl, G. R., Jan 2022, In: Biochemical Pharmacology. 195, 114868.

  Research output: Contribution to journal › Article › peer-review
  1 Scopus citations

• Structure activity studies of the melanocortin antagonist SHU9119 modified at the 6, 7, 8, and 9 positions

  Haskell-Luevano, C., Lim, S., Yuan, W., Cone, R. D. & Hruby, V. J., Jan 2000, In: Peptides. 21, 1, p. 49-57 9 p.

  Research output: Contribution to journal › Article › peer-review
  52 Scopus citations

• Structure-activity studies of the melanocortin peptides: Discovery of potent and selective affinity antagonists for the hMC3 and hMC4 receptors

  Grieco, P., Lavecchia, A., Cai, M., Trivedi, D., Weinberg, D., MacNeil, T., Van der Ploeg, L. H. T. & Hruby, V. J., Nov 21 2002, In: Journal of Medicinal Chemistry. 45, 24, p. 5287-5294 8 p.

  Research output: Contribution to journal › Article › peer-review
  69 Scopus citations

• Structure and Activation of Soluble Guanylyl Cyclase, the Nitric Oxide Sensor

  Montfort, W. R., Wales, J. A. & Weichsel, A., Jan 20 2017, In: Antioxidants and Redox Signaling. 26, 3, p. 107-121 15 p.

  Research output: Contribution to journal › Review article › peer-review
  71 Scopus citations

• Structure and age of the Lower Magdalena Valley basin basement, northern Colombia: New reflection-seismic and U-Pb-Hf insights into the termination of the central andes against the Caribbean basin

  Mora-Bohórquez, J. A., Ibánez-Mejia, M., Oncken, O., de Freitas, M., Vélez, V., Mesa, A. & Serna, L., Mar 1 2017, In: Journal of South American Earth Sciences. 74, p. 1-26 26 p.

  Research output: Contribution to journal › Article › peer-review
  31 Scopus citations

• Structure and architecture of the maize genome

  Haberer, G., Young, S., Bharti, A. K., Gundlach, H., Raymond, C., Fuks, G., Butler, E., Wing, R. A., Rounsley, S., Birren, B., Nusbaum, C., Mayer, K. F. X. & Messing, J., 2005, In: Plant physiology. 139, 4, p. 1612-1624 13 p.

  Research output: Contribution to journal › Article › peer-review
  115 Scopus citations

• Structure and behavior of the barringerite Ni end-member, Ni₂P, at deep Earth conditions and implications for natural Fe-Ni phosphides in planetary cores

  Dera, P., Lavina, B., Borkowski, L. A., Prakapenka, V. B., Sutton, S. R., Rivers, M. L., Downs, R. T., Boctor, N. Z. & Prewitt, C. T., Mar 4 2009, In: Journal of Geophysical Research: Solid Earth. 114, 3, B03201.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  18 Scopus citations

• Structure and Bonding of a Novel Mercuracycle Complex Containing B-Hg Bonds at Carborane Vertices

  Zheng, Z., Knobler, C. B., Curtis, C. E. & Hawthorne, M. F., Jan 1 1995, In: Inorganic Chemistry. 34, 2, p. 432-435 4 p.

  Research output: Contribution to journal › Article › peer-review
  32 Scopus citations

• Structure and cavity geometry optimization for ultrashort and high power pulse generation from a VECSEL

  Laurain, A., Rockmore, R., Baker, C. W., Kilen, I., Addamane, S., Balakrishnan, G., Hader, J., Perez, A. R., Stolz, W., Koch, S. W. & Moloney, J. V., 2018, Vertical External Cavity Surface Emitting Lasers (VECSELs) VIII. Chilla, J. L. (ed.). SPIE, 105150H. (Proceedings of SPIE - The International Society for Optical Engineering; vol. 10515).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
  1 Scopus citations

• Structure and Characterization of Flavolipids, a Novel Class of Biosurfactants Produced by Flavobacterium sp. Strain MTN11

  Bodour, A. A., Guerrero-Barajas, C., Jiorle, B. V., Malcomson, M. E., Paull, A. K., Somogyi, A., Trinh, L. N., Bates, R. B. & Maier, R. M., Jan 2004, In: Applied and environmental microbiology. 70, 1, p. 114-120 7 p.

  Research output: Contribution to journal › Article › peer-review
  98 Scopus citations

• Structure and composition of the neutral upper atmosphere of Mars from the MAVEN NGIMS investigation

  Mahaffy, P. R., Benna, M., Elrod, M., Yelle, R. V., Bougher, S. W., Stone, S. W. & Jakosky, B. M., Nov 16 2015, In: Geophysical Research Letters. 42, 21, p. 8951-8957 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  124 Scopus citations

• Structure and conformation of N⁴-hydroxycytosine and N⁴-hydroxy-5-fluorocytosine. A theoretical ab initio study

  Leś, A., Adamowicz, L. & Rode, W., Apr 29 1993, In: BBA - Gene Structure and Expression. 1173, 1, p. 39-48 10 p.

  Research output: Contribution to journal › Article › peer-review
  24 Scopus citations

• Structure and Connection: Comments on Sosa's Epistemology

  Cohen, S., Jan 14 2008, Ernest Sosa and his Critics. Wiley-Blackwell, p. 17-21 5 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
  3 Scopus citations

• Structure and decay modes of antisymmetric vibrations in the O(6) limit of the neutron-proton interacting boson model

  Barrett, B. R. & Otsuka, T., 1990, In: Physical Review C. 42, 6, p. 2438-2441 4 p.

  Research output: Contribution to journal › Article › peer-review
  5 Scopus citations

• Structure and development of antennae in a moth, Manduca sexta

  Sanes, J. R. & Hildebrand, J. G., Jul 15 1976, In: Developmental biology. 51, 2, p. 282-299 18 p.

  Research output: Contribution to journal › Article › peer-review
  167 Scopus citations

• Structure and disorder in squaraine-C₆₀ organic solar cells: A theoretical description of molecular packing and electronic coupling at the donor-acceptor interface

  Fu, Y. T., Da Silva Filho, D. A., Sini, G., Asiri, A. M., Aziz, S. G., Risko, C. & Brédas, J. L., Jun 25 2014, In: Advanced Functional Materials. 24, 24, p. 3790-3798 9 p.

  Research output: Contribution to journal › Article › peer-review
  43 Scopus citations

• Structure and dynamics of a CheY-binding domain of the chemotaxis kinase CheA determined by nuclear magnetic resonance spectroscopy

  McEvoy, M. M., Muhandiram, D. R., Kay, L. E. & Dahlquist, F. W., May 7 1996, In: Biochemistry. 35, 18, p. 5633-5640 8 p.

  Research output: Contribution to journal › Article › peer-review
  43 Scopus citations

• Structure and dynamics of breaking foams

  Burnett, G. D., Chae, J. J., Tam, W. Y., De Almeida, R. M. C. & Tabor, M., 1995, In: Physical Review E. 51, 6, p. 5788-5796 9 p.

  Research output: Contribution to journal › Article › peer-review
  24 Scopus citations

• Structure and dynamics of the antitumor drugs nogalamycin and disnogalamycin complexed to d(CGTACG)₂: comparison of crystal and solution structures

  Robinson, H., Yang, D. & Wang, A. H. J., Nov 4 1994, In: Gene. 149, 1, p. 179-188 10 p.

  Research output: Contribution to journal › Article › peer-review
  10 Scopus citations

• Structure and dynamics of α-MSH using DRISM integral equation theory and stochastic dynamics

  Prabhu, N. V., Perkyns, J. S., Pettitt, B. M. & Hruby, V. J., Sep 1999, In: Biopolymers. 50, 3, p. 255-272 18 p.

  Research output: Contribution to journal › Article › peer-review
  17 Scopus citations

• Structure and energy of nucleic acid base-amino acid complexes: 1. 1- methyl-uracil-acrylamide

  Galetich, I., Kosevich, M., Shelkovsky, V., Stepanian, S. G., Blagoi, Y. P. & Adamowicz, L., Mar 1 1999, In: Journal of Molecular Structure. 478, 1-3, p. 155-162 8 p.

  Research output: Contribution to journal › Article › peer-review
  17 Scopus citations

• Structure and evolution of debris disks around F-type stars. I. observations, database, and basic evolutionary aspects

  Moór, A., Pascucci, I., Kóspál, Á., Ábrahám, P., Csengeri, T., Kiss, L. L., Apai, D., Grady, C., Henning, T., Kiss, C., Bayliss, D., Juhász, A., Kovcs, J. & Szalai, T., Mar 2011, In: Astrophysical Journal, Supplement Series. 193, 1, 4.

  Research output: Contribution to journal › Article › peer-review
  63 Scopus citations

• Structure and Evolution of Internally Heated Hot Jupiters

  Komacek, T. D. & Youdin, A. N., Aug 1 2017, In: Astrophysical Journal. 844, 2, 94.

  Research output: Contribution to journal › Article › peer-review
  27 Scopus citations

• Structure and evolution of protoplanetary disks

  Dullemond, C., Pavlyuchenkov, Y., Apai, D. & Pontoppidan, K., 2008, In: Journal of Physics: Conference Series. 131, 012018.

  Research output: Contribution to journal › Article › peer-review
  1 Scopus citations