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Structure-activity relationship of biphalin. The synthesis and biological activities of new analogues with modifications in positions 3 and 4
Misicka, A., Lipkowski, A. W., Horvath, R., Davis, P., Porreca, F., Yamamura, H. I. & Hruby, V. J., Mar 7 1997, In: Life Sciences. 60, 15, p. 1263-1269 7 p.Research output: Contribution to journal › Article › peer-review
35 Scopus citations -
Structure–Activity Relationships and Transcriptomic Analysis of Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors
Poloznikov, A. A., Nikulin, S. V., Hushpulian, D. M., Khristichenko, A. Y., Osipyants, A. I., Asachenko, A. F., Shurupova, O. V., Savin, S. S., Lee, S. H., Gaisina, I. N., Thatcher, G. R. J., Narciso, A., Chang, E. P., Kazakov, S. V., Krucher, N., Tishkov, V. I., Thomas, B. & Gazaryan, I. G., Feb 2022, In: Antioxidants. 11, 2, 220.Research output: Contribution to journal › Article › peer-review
Open Access -
Structure-activity relationships for a family of benzothiophene selective estrogen receptor modulators including raloxifene and arzoxifene
Overk, C. R., Peng, K. W., Asghodom, R. T., Kastrati, I., Lantvit, D. D., Qin, Z., Frasor, J., Bolton, J. L. & Thatcher, G. R. J., Oct 8 2007, In: ChemMedChem. 2, 10, p. 1520-1526 7 p.Research output: Contribution to journal › Article › peer-review
35 Scopus citations -
Structure-activity relationships for SNC80 and related compounds at cloned human delta and mu opioid receptors
Knapp, R. J., Santoro, G., De Leon, I. A., Lee, K. B., Edsall, S. A., Waite, S., Malatynska, E., Varga, E., Calderon, S. N., Rice, K. C., Rothman, R. B., Porreca, F., Roeske, W. R. & Yamamura, H. I., Jun 1996, In: Journal of Pharmacology and Experimental Therapeutics. 277, 3, p. 1284-1291 8 p.Research output: Contribution to journal › Article › peer-review
62 Scopus citations -
Structure-activity relationships for withanolides as inducers of the cellular heat-shock response
Wijeratne, E. M. K., Xu, Y. M., Scherz-Shouval, R., Marron, M. T., Rocha, D. D., Liu, M. X., Costa-Lotufo, L. V., Santagata, S., Lindquist, S., Whitesell, L. & Gunatilaka, A. A. L., Apr 10 2014, In: Journal of Medicinal Chemistry. 57, 7, p. 2851-2863 13 p.Research output: Contribution to journal › Article › peer-review
46 Scopus citations -
Structure-Activity Relationships of (+)-CC-1065 Analogues in the Inhibition of Helicase-Catalyzed Unwinding of Duplex DNA
Sun, D. & Hurley, L. H., May 1 1992, In: Journal of Medicinal Chemistry. 35, 10, p. 1773-1782 10 p.Research output: Contribution to journal › Article › peer-review
21 Scopus citations -
Structure-Activity Relationships of [des-Arg7]Dynorphin A Analogues at the ΰ Opioid Receptor
Ramos-Colon, C. N., Lee, Y. S., Remesic, M., Hall, S. M., Lavigne, J., Davis, P., Sandweiss, A. J., McIntosh, M. I., Hanson, J., Largent-Milnes, T. M., Vanderah, T. W., Streicher, J., Porreca, F. & Hruby, V. J., Nov 23 2016, In: Journal of Medicinal Chemistry. 59, 22, p. 10291-10298 8 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
Structure‐Activity Relationships of [Nle4, D‐Phe7]α‐MSH: Discovery of a Tripeptidyl Agonist Exhibiting Sustained Bioactivity
SAWYER, TOMI. K., CASTRUCCI, ANA. M., STAPLES, DOUGLAS. J., AFFHOLTER, JOSEPH. A., DE VAUX, ANNE. E., HRUBY, VICTOR. J. & HADLEY, MAC. E., May 1993, In: Annals of the New York Academy of Sciences. 680, 1, p. 597-599 3 p.Research output: Contribution to journal › Article › peer-review
38 Scopus citations -
Structure-activity relationships of analogues of higly potent opioid peptide, biphalin
Misicka, A., Lipkowski, A. W., Horvath, R., Davis, P., Porreca, F., Yamamura, H. I. & Hruby, V. J., Feb 21 1994, In: Regulatory Peptides. 53, SUPPL. 1, p. S131-S132Research output: Contribution to journal › Article › peer-review
7 Scopus citations -
Structure-activity relationships of a series of [D-Ala2]deltorphin I and II analogues; in vitro blood-brain barrier permeability and stability
Thomas, S. A., Abbruscato, T. J., Hau, V. S., Gillespie, T. J., Zsigo, J., Hruby, V. J. & Davis, T. P., May 1997, In: Journal of Pharmacology and Experimental Therapeutics. 281, 2, p. 817-825 9 p.Research output: Contribution to journal › Article › peer-review
35 Scopus citations -
Structure-activity relationships of bifunctional cyclic disulfide peptides based on overlapping pharmacophores at opioid and cholecystokinin receptors
Agnes, R. S., Ying, J., Kövér, K. E., Lee, Y. S., Davis, P., Ma, S. W., Badghisi, H., Porreca, F., Lai, J. & Hruby, V. J., Aug 2008, In: Peptides. 29, 8, p. 1413-1423 11 p.Research output: Contribution to journal › Article › peer-review
19 Scopus citations -
Structure-activity relationships of bifunctional peptides based on overlapping pharmacophores at opioid and cholecystokinin receptors
Agnes, R. S., Lee, Y. S., Davis, P., Ma, S. W., Badghisi, H., Porreca, F., Lai, J. & Hruby, V. J., May 18 2006, In: Journal of Medicinal Chemistry. 49, 10, p. 2868-2875 8 p.Research output: Contribution to journal › Article › peer-review
40 Scopus citations -
Structure-activity relationships of cyclic lactam analogues of α-melanocyte-stimulating hormone (α-MSH) targeting the human melanocortin-3 receptor
Mayorov, A. V., Cai, M., Palmer, E. S., Dedek, M. M., Cain, J. P., Van Scoy, A. R., Tan, B., Vagner, J., Trivedi, D. & Hruby, V. J., Jan 24 2008, In: Journal of Medicinal Chemistry. 51, 2, p. 187-195 9 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
Structure-activity relationships of diphenylpiperazine N-type calcium channel inhibitors
Pajouhesh, H., Feng, Z. P., Ding, Y., Zhang, L., Pajouhesh, H., Morrison, J. L., Belardetti, F., Tringham, E., Simonson, E., Vanderah, T. W., Porreca, F., Zamponi, G. W., Mitscher, L. A. & Snutch, T. P., Feb 15 2010, In: Bioorganic and Medicinal Chemistry Letters. 20, 4, p. 1378-1383 6 p.Research output: Contribution to journal › Article › peer-review
36 Scopus citations -
Structure-activity relationships of non-opioid [des-Arg7]-dynorphin A analogues for bradykinin receptors
Lee, Y. S., Rankin, D., Hall, S. M., Ramos-Colon, C., Ortiz, J. J., Kupp, R., Porreca, F., Lai, J. & Hruby, V. J., Nov 1 2014, In: Bioorganic and Medicinal Chemistry Letters. 24, 21, p. 4976-4979 4 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
Structure-activity relationships of novel cyclic α-MSH/β-MSH hybrid analogues that lead to potent and selective ligands for the human MC3R and human MC5R
Balse-Srinivasan, P., Grieco, P., Cai, M., Trivedi, D. & Hruby, V. J., Aug 14 2003, In: Journal of Medicinal Chemistry. 46, 17, p. 3728-3733 6 p.Research output: Contribution to journal › Article › peer-review
28 Scopus citations -
Structure-activity relationships of trimethoxybenzyl piperazine N-type calcium channel inhibitors
Pajouhesh, H., Feng, Z. P., Zhang, L., Pajouhesh, H., Jiang, X., Hendricson, A., Dong, H., Tringham, E., Ding, Y., Vanderah, T. W., Porreca, F., Belardetti, F., Zamponi, G. W., Mitscher, L. A. & Snutch, T. P., Jun 15 2012, In: Bioorganic and Medicinal Chemistry Letters. 22, 12, p. 4153-4158 6 p.Research output: Contribution to journal › Article › peer-review
20 Scopus citations -
Structure-Activity Relationships of Withanolides as Antiproliferative Agents for Multiple Myeloma: Comparison of Activity in 2D Models and a 3D Coculture Model
Freitas Misakyan, M. F., Wijeratne, E. M. K., Issa, M. E., Xu, Y. M., Monteillier, A., Gunatilaka, A. A. L. & Cuendet, M., Aug 27 2021, In: Journal Of Natural Products. 84, 8, p. 2321-2335 15 p.Research output: Contribution to journal › Article › peer-review
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Structure-Activity Relationships of γ-MSH Analogues at the Human Melanocortin MC3, MC4, and MC5 Receptors. Discovery of Highly Selective hMC3R, hMC4R, and hMC5R Analogues
Balse-Srinivasan, P., Grieco, P., Cai, M., Trivedi, D. & Hruby, V. J., Nov 6 2003, In: Journal of Medicinal Chemistry. 46, 23, p. 4965-4973 9 p.Research output: Contribution to journal › Article › peer-review
24 Scopus citations -
Structure-activity relationship study of growth inhibitory 2-styrylchromones against carcinoma cells
Lin, C., Lu, P. J., Yang, C. N., Hulme, C. & Shaw, A. Y., May 2013, In: Medicinal Chemistry Research. 22, 5, p. 2385-2394 10 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
Structure-activity relations of the cardiac gap junction channel
Spray, D. C. & Burt, J. M., 1990, In: American Journal of Physiology - Cell Physiology. 258, 2 27-2, p. C195-C205Research output: Contribution to journal › Review article › peer-review
248 Scopus citations -
Structure-Activity Studies of a Novel Bicyclic Oxytocin Antagonist
Smith, D. D., Slaninova, J. & Hruby, V. J., May 1 1992, In: Journal of Medicinal Chemistry. 35, 9, p. 1558-1563 6 p.Research output: Contribution to journal › Article › peer-review
39 Scopus citations -
Structure-Activity Studies of Highly Potent Cyclic [formula omitted]Melanotropin Analogues
Knittel, J. J., Sawyer, T. K., Hruby, V. J. & Hadley, M. E., Feb 1983, In: Journal of Medicinal Chemistry. 26, 2, p. 125-129 5 p.Research output: Contribution to journal › Article › peer-review
42 Scopus citations -
Structure-activity studies of hydrophobic amino acid replacements at positions 9, 11 and 16 of glucagon
Sturm, N. S., Hutzler, A. M., David, C. S., Azizeh, B. Y., Trivedi, D. & Hruby, V. J., 1997, In: Journal of Peptide Research. 49, 4, p. 293-299 7 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Structure-activity studies of new melanocortin peptides containing an aromatic amino acid at the N-terminal position
Grieco, P., Cai, M., Mayorov, A. V., Trivedi, D. & Hruby, V. J., Feb 2006, In: Peptides. 27, 2, p. 472-481 10 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
Structure-activity studies of peptides from the "hot-spot" region of human CD2 protein: Development of peptides for immunomodulation
Liu, J., Ying, J., Chow, V. T. K., Hruby, V. J. & Satyanarayanajois, S. D., Oct 6 2005, In: Journal of Medicinal Chemistry. 48, 20, p. 6236-6249 14 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
Structure-activity studies of PTPRD phosphatase inhibitors identify a 7-cyclopentymethoxy illudalic acid analog candidate for development
Henderson, I. M., Zeng, F., Bhuiyan, N. H., Luo, D., Martinez, M., Smoake, J., Bi, F., Perera, C., Johnson, D., Prisinzano, T. E., Wang, W. & Uhl, G. R., Jan 2022, In: Biochemical Pharmacology. 195, 114868.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Structure activity studies of the melanocortin antagonist SHU9119 modified at the 6, 7, 8, and 9 positions
Haskell-Luevano, C., Lim, S., Yuan, W., Cone, R. D. & Hruby, V. J., Jan 2000, In: Peptides. 21, 1, p. 49-57 9 p.Research output: Contribution to journal › Article › peer-review
52 Scopus citations -
Structure-activity studies of the melanocortin peptides: Discovery of potent and selective affinity antagonists for the hMC3 and hMC4 receptors
Grieco, P., Lavecchia, A., Cai, M., Trivedi, D., Weinberg, D., MacNeil, T., Van der Ploeg, L. H. T. & Hruby, V. J., Nov 21 2002, In: Journal of Medicinal Chemistry. 45, 24, p. 5287-5294 8 p.Research output: Contribution to journal › Article › peer-review
69 Scopus citations -
Structure and Activation of Soluble Guanylyl Cyclase, the Nitric Oxide Sensor
Montfort, W. R., Wales, J. A. & Weichsel, A., Jan 20 2017, In: Antioxidants and Redox Signaling. 26, 3, p. 107-121 15 p.Research output: Contribution to journal › Review article › peer-review
71 Scopus citations -
Structure and age of the Lower Magdalena Valley basin basement, northern Colombia: New reflection-seismic and U-Pb-Hf insights into the termination of the central andes against the Caribbean basin
Mora-Bohórquez, J. A., Ibánez-Mejia, M., Oncken, O., de Freitas, M., Vélez, V., Mesa, A. & Serna, L., Mar 1 2017, In: Journal of South American Earth Sciences. 74, p. 1-26 26 p.Research output: Contribution to journal › Article › peer-review
31 Scopus citations -
Structure and architecture of the maize genome
Haberer, G., Young, S., Bharti, A. K., Gundlach, H., Raymond, C., Fuks, G., Butler, E., Wing, R. A., Rounsley, S., Birren, B., Nusbaum, C., Mayer, K. F. X. & Messing, J., 2005, In: Plant physiology. 139, 4, p. 1612-1624 13 p.Research output: Contribution to journal › Article › peer-review
115 Scopus citations -
Structure and behavior of the barringerite Ni end-member, Ni2P, at deep Earth conditions and implications for natural Fe-Ni phosphides in planetary cores
Dera, P., Lavina, B., Borkowski, L. A., Prakapenka, V. B., Sutton, S. R., Rivers, M. L., Downs, R. T., Boctor, N. Z. & Prewitt, C. T., Mar 4 2009, In: Journal of Geophysical Research: Solid Earth. 114, 3, B03201.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
Structure and Bonding of a Novel Mercuracycle Complex Containing B-Hg Bonds at Carborane Vertices
Zheng, Z., Knobler, C. B., Curtis, C. E. & Hawthorne, M. F., Jan 1 1995, In: Inorganic Chemistry. 34, 2, p. 432-435 4 p.Research output: Contribution to journal › Article › peer-review
32 Scopus citations -
Structure and cavity geometry optimization for ultrashort and high power pulse generation from a VECSEL
Laurain, A., Rockmore, R., Baker, C. W., Kilen, I., Addamane, S., Balakrishnan, G., Hader, J., Perez, A. R., Stolz, W., Koch, S. W. & Moloney, J. V., 2018, Vertical External Cavity Surface Emitting Lasers (VECSELs) VIII. Chilla, J. L. (ed.). SPIE, 105150H. (Proceedings of SPIE - The International Society for Optical Engineering; vol. 10515).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
1 Scopus citations -
Structure and Characterization of Flavolipids, a Novel Class of Biosurfactants Produced by Flavobacterium sp. Strain MTN11
Bodour, A. A., Guerrero-Barajas, C., Jiorle, B. V., Malcomson, M. E., Paull, A. K., Somogyi, A., Trinh, L. N., Bates, R. B. & Maier, R. M., Jan 2004, In: Applied and environmental microbiology. 70, 1, p. 114-120 7 p.Research output: Contribution to journal › Article › peer-review
98 Scopus citations -
Structure and composition of the neutral upper atmosphere of Mars from the MAVEN NGIMS investigation
Mahaffy, P. R., Benna, M., Elrod, M., Yelle, R. V., Bougher, S. W., Stone, S. W. & Jakosky, B. M., Nov 16 2015, In: Geophysical Research Letters. 42, 21, p. 8951-8957 7 p.Research output: Contribution to journal › Article › peer-review
Open Access124 Scopus citations -
Structure and conformation of N4-hydroxycytosine and N4-hydroxy-5-fluorocytosine. A theoretical ab initio study
Leś, A., Adamowicz, L. & Rode, W., Apr 29 1993, In: BBA - Gene Structure and Expression. 1173, 1, p. 39-48 10 p.Research output: Contribution to journal › Article › peer-review
24 Scopus citations -
Structure and Connection: Comments on Sosa's Epistemology
Cohen, S., Jan 14 2008, Ernest Sosa and his Critics. Wiley-Blackwell, p. 17-21 5 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
3 Scopus citations -
Structure and decay modes of antisymmetric vibrations in the O(6) limit of the neutron-proton interacting boson model
Barrett, B. R. & Otsuka, T., 1990, In: Physical Review C. 42, 6, p. 2438-2441 4 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Structure and development of antennae in a moth, Manduca sexta
Sanes, J. R. & Hildebrand, J. G., Jul 15 1976, In: Developmental biology. 51, 2, p. 282-299 18 p.Research output: Contribution to journal › Article › peer-review
167 Scopus citations -
Structure and disorder in squaraine-C60 organic solar cells: A theoretical description of molecular packing and electronic coupling at the donor-acceptor interface
Fu, Y. T., Da Silva Filho, D. A., Sini, G., Asiri, A. M., Aziz, S. G., Risko, C. & Brédas, J. L., Jun 25 2014, In: Advanced Functional Materials. 24, 24, p. 3790-3798 9 p.Research output: Contribution to journal › Article › peer-review
43 Scopus citations -
Structure and dynamics of a CheY-binding domain of the chemotaxis kinase CheA determined by nuclear magnetic resonance spectroscopy
McEvoy, M. M., Muhandiram, D. R., Kay, L. E. & Dahlquist, F. W., May 7 1996, In: Biochemistry. 35, 18, p. 5633-5640 8 p.Research output: Contribution to journal › Article › peer-review
43 Scopus citations -
Structure and dynamics of breaking foams
Burnett, G. D., Chae, J. J., Tam, W. Y., De Almeida, R. M. C. & Tabor, M., 1995, In: Physical Review E. 51, 6, p. 5788-5796 9 p.Research output: Contribution to journal › Article › peer-review
24 Scopus citations -
Structure and dynamics of the antitumor drugs nogalamycin and disnogalamycin complexed to d(CGTACG)2: comparison of crystal and solution structures
Robinson, H., Yang, D. & Wang, A. H. J., Nov 4 1994, In: Gene. 149, 1, p. 179-188 10 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
Structure and dynamics of α-MSH using DRISM integral equation theory and stochastic dynamics
Prabhu, N. V., Perkyns, J. S., Pettitt, B. M. & Hruby, V. J., Sep 1999, In: Biopolymers. 50, 3, p. 255-272 18 p.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
Structure and energy of nucleic acid base-amino acid complexes: 1. 1- methyl-uracil-acrylamide
Galetich, I., Kosevich, M., Shelkovsky, V., Stepanian, S. G., Blagoi, Y. P. & Adamowicz, L., Mar 1 1999, In: Journal of Molecular Structure. 478, 1-3, p. 155-162 8 p.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
Structure and evolution of debris disks around F-type stars. I. observations, database, and basic evolutionary aspects
Moór, A., Pascucci, I., Kóspál, Á., Ábrahám, P., Csengeri, T., Kiss, L. L., Apai, D., Grady, C., Henning, T., Kiss, C., Bayliss, D., Juhász, A., Kovcs, J. & Szalai, T., Mar 2011, In: Astrophysical Journal, Supplement Series. 193, 1, 4.Research output: Contribution to journal › Article › peer-review
63 Scopus citations -
Structure and Evolution of Internally Heated Hot Jupiters
Komacek, T. D. & Youdin, A. N., Aug 1 2017, In: Astrophysical Journal. 844, 2, 94.Research output: Contribution to journal › Article › peer-review
27 Scopus citations -
Structure and evolution of protoplanetary disks
Dullemond, C., Pavlyuchenkov, Y., Apai, D. & Pontoppidan, K., 2008, In: Journal of Physics: Conference Series. 131, 012018.Research output: Contribution to journal › Article › peer-review
1 Scopus citations