3D T2-weighted spin echo imaging in the breast

Catherine J. Moran, Brian A. Hargreaves, Manojkumar Saranathan, Jafi A. Lipson, Jennifer Kao, Debra M. Ikeda, Bruce L. Daniel

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Purpose To evaluate the performance of 2D versus 3D T2-weighted spin echo imaging in the breast. Materials and Methods 2D and 3D T2-weighted images were acquired in 25 patients as part of a clinically indicated breast magnetic resonance imaging (MRI) exam. Lesion-to-fibroglandular tissue signal ratio was measured in 16 identified lesions. Clarity of lesion morphology was assessed through a blinded review by three radiologists. Instances demonstrating the potential diagnostic contribution of 3D versus 2D T2-weighted imaging in the breast were noted through unblinded review by a fourth radiologist. Results The lesion-to-fibroglandular tissue signal ratio was well correlated between 2D and 3D T2-weighted images (R2 = 0.93). Clarity of lesion morphology was significantly better with 3D T2-weighted imaging for all observers based on a McNemar test (P ≤ 0.02, P ≤ 0.01, P ≤ 0.03). Instances indicating the potential diagnostic contribution of 3D T2-weighted imaging included improved depiction of signal intensity and improved alignment between DCE and T2-weighted findings. Conclusion In this pilot study, 3D T2-weighted imaging provided comparable contrast and improved depiction of lesion morphology in the breast in comparison to 2D T2-weighted imaging. Based on these results further investigation to determine the diagnostic impact of 3D T2-weighted imaging in breast MRI is warranted.

Original languageEnglish (US)
Pages (from-to)332-338
Number of pages7
JournalJournal of Magnetic Resonance Imaging
Volume39
Issue number2
DOIs
StatePublished - Feb 2014
Externally publishedYes

Keywords

  • breast imaging
  • extended echo train
  • high-resolution
  • spin-echo
  • T2-weighted
  • three-dimensional

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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