2023 HRS/APHRS/LAHRS guideline on cardiac physiologic pacing for the avoidance and mitigation of heart failure

Mina K. Chung, Kristen K. Patton, Chu Pak Lau, Alexander R.J. Dal Forno, Sana M. Al-Khatib, Vanita Arora, Ulrika Maria Birgersdotter-Green, Yong Mei Cha, Eugene H. Chung, Edmond M. Cronin, Anne B. Curtis, Iwona Cygankiewicz, Gopi Dandamudi, Anne M. Dubin, Douglas P. Ensch, Taya V. Glotzer, Michael R. Gold, Zachary D. Goldberger, Rakesh Gopinathannair, Eiran Z. GorodeskiAlejandra Gutierrez, Juan C. Guzman, Weijian Huang, Peter B. Imrey, Julia H. Indik, Saima Karim, Peter P. Karpawich, Yaariv Khaykin, Erich L. Kiehl, Jordana Kron, Valentina Kutyifa, Mark S. Link, Joseph E. Marine, Wilfried Mullens, Seung Jung Park, Ratika Parkash, Manuel F. Patete, Rajeev Kumar Pathak, Carlos A. Perona, John Rickard, Mark H. Schoenfeld, Swee Chong Seow, Win Kuang Shen, Morio Shoda, Jagmeet P. Singh, David J. Slotwiner, Arun Raghav M. Sridhar, Uma N. Srivatsa, Eric C. Stecker, Tanyanan Tanawuttiwat, W. H.Wilson Tang, Carlos Andres Tapias, Cynthia M. Tracy, Gaurav A. Upadhyay, Niraj Varma, Kevin Vernooy, Pugazhendhi Vijayaraman, Sarah Ann Worsnick, Wojciech Zareba, Emily P. Zeitler

Research output: Contribution to journalArticlepeer-review

90 Scopus citations


Cardiac physiologic pacing (CPP), encompassing cardiac resynchronization therapy (CRT) and conduction system pacing (CSP), has emerged as a pacing therapy strategy that may mitigate or prevent the development of heart failure (HF) in patients with ventricular dyssynchrony or pacing-induced cardiomyopathy. This clinical practice guideline is intended to provide guidance on indications for CRT for HF therapy and CPP in patients with pacemaker indications or HF, patient selection, pre-procedure evaluation and preparation, implant procedure management, follow-up evaluation and optimization of CPP response, and use in pediatric populations. Gaps in knowledge, pointing to new directions for future research, are also identified.

Original languageEnglish (US)
Pages (from-to)e17-e91
JournalHeart Rhythm
Issue number9
StatePublished - Sep 2023


  • Cardiac resynchronization therapy
  • Conduction system pacing
  • Guideline
  • His bundle pacing
  • Left bundle branch area pacing

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Physiology (medical)


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