2-Chloro-1,4-dimethoxybenzene as a mediator of lignin peroxidase catalyzed oxidations

Pauline J.M. Teunissen; Jim A. Field

doi:10.1016/S0014-5793(98)01386-6

2-Chloro-1,4-dimethoxybenzene as a mediator of lignin peroxidase catalyzed oxidations

Pauline J.M. Teunissen
, Jim A. Field

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Abstract

Poly R-478, 4-methoxymandelic acid and oxalic acid were oxidized by lignin peroxidase (LiP) in the presence of the fungal metabolite 2-chloro-1,4-dimethoxybenzene (2Cl-14DMB), whereas no oxidation occurred in the absence of 2Cl-14DMB. These substrates clearly inhibited the consumption of 2Cl-14DMB and the formation of 2-chloro-1,4-benzoquinone from 2Cl-14DMB by LiP. The results suggest that 2Cl-14DMB can replace the function of veratryl alcohol as a redox mediator in lignin peroxidase catalyzed oxidations. Copyright (C) 1998 Federation of European Biochemical Societies.

Original language	English (US)
Pages (from-to)	219-223
Number of pages	5
Journal	FEBS Letters
Volume	439
Issue number	3
DOIs	https://doi.org/10.1016/S0014-5793(98)01386-6
State	Published - Nov 20 1998
Externally published	Yes

Keywords

2-Chloro-1,4-dimethoxybenzene
4-Methoxy mandelic acid
Bjerkandera sp. BOS55
Lignin peroxidase
Mediator
Poly R-478

ASJC Scopus subject areas

Biophysics
Structural Biology
Biochemistry
Molecular Biology
Genetics
Cell Biology

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10.1016/S0014-5793(98)01386-6

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@article{dbf2b7802df142f3b4326adad7d40731,

title = "2-Chloro-1,4-dimethoxybenzene as a mediator of lignin peroxidase catalyzed oxidations",

abstract = "Poly R-478, 4-methoxymandelic acid and oxalic acid were oxidized by lignin peroxidase (LiP) in the presence of the fungal metabolite 2-chloro-1,4-dimethoxybenzene (2Cl-14DMB), whereas no oxidation occurred in the absence of 2Cl-14DMB. These substrates clearly inhibited the consumption of 2Cl-14DMB and the formation of 2-chloro-1,4-benzoquinone from 2Cl-14DMB by LiP. The results suggest that 2Cl-14DMB can replace the function of veratryl alcohol as a redox mediator in lignin peroxidase catalyzed oxidations. Copyright (C) 1998 Federation of European Biochemical Societies.",

keywords = "2-Chloro-1,4-dimethoxybenzene, 4-Methoxy mandelic acid, Bjerkandera sp. BOS55, Lignin peroxidase, Mediator, Poly R-478",

author = "Teunissen, \{Pauline J.M.\} and Field, \{Jim A.\}",

note = "Funding Information: The research reported here was supported by the Life Science Foundation (SLW), which is subsidized by the Netherlands Organization for Scientific Research (NWO).",

year = "1998",

month = nov,

day = "20",

doi = "10.1016/S0014-5793(98)01386-6",

language = "English (US)",

volume = "439",

pages = "219--223",

journal = "FEBS Letters",

issn = "0014-5793",

publisher = "John Wiley and Sons Inc.",

number = "3",

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TY - JOUR

T1 - 2-Chloro-1,4-dimethoxybenzene as a mediator of lignin peroxidase catalyzed oxidations

AU - Teunissen, Pauline J.M.

AU - Field, Jim A.

N1 - Funding Information: The research reported here was supported by the Life Science Foundation (SLW), which is subsidized by the Netherlands Organization for Scientific Research (NWO).

PY - 1998/11/20

Y1 - 1998/11/20

N2 - Poly R-478, 4-methoxymandelic acid and oxalic acid were oxidized by lignin peroxidase (LiP) in the presence of the fungal metabolite 2-chloro-1,4-dimethoxybenzene (2Cl-14DMB), whereas no oxidation occurred in the absence of 2Cl-14DMB. These substrates clearly inhibited the consumption of 2Cl-14DMB and the formation of 2-chloro-1,4-benzoquinone from 2Cl-14DMB by LiP. The results suggest that 2Cl-14DMB can replace the function of veratryl alcohol as a redox mediator in lignin peroxidase catalyzed oxidations. Copyright (C) 1998 Federation of European Biochemical Societies.

AB - Poly R-478, 4-methoxymandelic acid and oxalic acid were oxidized by lignin peroxidase (LiP) in the presence of the fungal metabolite 2-chloro-1,4-dimethoxybenzene (2Cl-14DMB), whereas no oxidation occurred in the absence of 2Cl-14DMB. These substrates clearly inhibited the consumption of 2Cl-14DMB and the formation of 2-chloro-1,4-benzoquinone from 2Cl-14DMB by LiP. The results suggest that 2Cl-14DMB can replace the function of veratryl alcohol as a redox mediator in lignin peroxidase catalyzed oxidations. Copyright (C) 1998 Federation of European Biochemical Societies.

KW - 2-Chloro-1,4-dimethoxybenzene

KW - 4-Methoxy mandelic acid

KW - Bjerkandera sp. BOS55

KW - Lignin peroxidase

KW - Mediator

KW - Poly R-478

UR - https://www.scopus.com/pages/publications/0031790634

UR - https://www.scopus.com/pages/publications/0031790634#tab=citedBy

U2 - 10.1016/S0014-5793(98)01386-6

DO - 10.1016/S0014-5793(98)01386-6

M3 - Article

C2 - 9845326

AN - SCOPUS:0031790634

SN - 0014-5793

VL - 439

SP - 219

EP - 223

JO - FEBS Letters

JF - FEBS Letters

IS - 3

ER -

2-Chloro-1,4-dimethoxybenzene as a mediator of lignin peroxidase catalyzed oxidations

Abstract

Keywords

ASJC Scopus subject areas

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