1,3-Benzodithiole-1,1,3,3-tetraoxide (BDT) as a versatile methylation reagent in catalytic enantioselective Michael addition reaction with enals

Shilei Zhang, Jian Li, Sihan Zhao, Wei Wang

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

A protocol of an organocatalytic highly enantioselective conjugate addition of nucleophilic BDT to enals has been developed and the versatile Michael adducts serve as useful building blocks for a variety of organic transformations.

Original languageEnglish (US)
Pages (from-to)1766-1769
Number of pages4
JournalTetrahedron Letters
Volume51
Issue number13
DOIs
StatePublished - Mar 31 2010
Externally publishedYes

Keywords

  • Methylation
  • Michael
  • Organocatalysis

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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