1,3-Benzodithiole-1,1,3,3-tetraoxide (BDT) as a versatile methylation reagent in catalytic enantioselective Michael addition reaction with enals

Shilei Zhang; Jian Li; Sihan Zhao; Wei Wang

doi:10.1016/j.tetlet.2010.01.102

1,3-Benzodithiole-1,1,3,3-tetraoxide (BDT) as a versatile methylation reagent in catalytic enantioselective Michael addition reaction with enals

Shilei Zhang, Jian Li, Sihan Zhao, Wei Wang

Research output: Contribution to journal › Article › peer-review

20 Scopus citations

Abstract

A protocol of an organocatalytic highly enantioselective conjugate addition of nucleophilic BDT to enals has been developed and the versatile Michael adducts serve as useful building blocks for a variety of organic transformations.

Original language	English (US)
Pages (from-to)	1766-1769
Number of pages	4
Journal	Tetrahedron Letters
Volume	51
Issue number	13
DOIs	https://doi.org/10.1016/j.tetlet.2010.01.102
State	Published - Mar 31 2010
Externally published	Yes

Keywords

Methylation
Michael
Organocatalysis

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/j.tetlet.2010.01.102

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title = "1,3-Benzodithiole-1,1,3,3-tetraoxide (BDT) as a versatile methylation reagent in catalytic enantioselective Michael addition reaction with enals",

abstract = "A protocol of an organocatalytic highly enantioselective conjugate addition of nucleophilic BDT to enals has been developed and the versatile Michael adducts serve as useful building blocks for a variety of organic transformations.",

keywords = "Methylation, Michael, Organocatalysis",

author = "Shilei Zhang and Jian Li and Sihan Zhao and Wei Wang",

year = "2010",

month = mar,

day = "31",

doi = "10.1016/j.tetlet.2010.01.102",

language = "English (US)",

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journal = "Tetrahedron Letters",

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T1 - 1,3-Benzodithiole-1,1,3,3-tetraoxide (BDT) as a versatile methylation reagent in catalytic enantioselective Michael addition reaction with enals

AU - Zhang, Shilei

AU - Li, Jian

AU - Zhao, Sihan

AU - Wang, Wei

PY - 2010/3/31

Y1 - 2010/3/31

N2 - A protocol of an organocatalytic highly enantioselective conjugate addition of nucleophilic BDT to enals has been developed and the versatile Michael adducts serve as useful building blocks for a variety of organic transformations.

AB - A protocol of an organocatalytic highly enantioselective conjugate addition of nucleophilic BDT to enals has been developed and the versatile Michael adducts serve as useful building blocks for a variety of organic transformations.

KW - Methylation

KW - Michael

KW - Organocatalysis

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U2 - 10.1016/j.tetlet.2010.01.102

DO - 10.1016/j.tetlet.2010.01.102

M3 - Article

AN - SCOPUS:76949094244

SN - 0040-4039

VL - 51

SP - 1766

EP - 1769

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 13

ER -

1,3-Benzodithiole-1,1,3,3-tetraoxide (BDT) as a versatile methylation reagent in catalytic enantioselective Michael addition reaction with enals

Abstract

Keywords

ASJC Scopus subject areas

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