Keyphrases
Molecular Mechanism
83%
Genetic Mechanism
70%
Hypoxia-induced Pulmonary Hypertension
66%
Pulmonary Artery Smooth muscle Cells (PASMCs)
66%
Hypoxia
62%
TRP Channels
36%
Kv Channels
36%
Notch Signaling
24%
Hypoxia Tolerance
16%
Notch Signaling Pathway
16%
Pulmonary Vascular Remodeling
13%
Ion Channels
13%
Signaling Genes
12%
Chronic Obstructive Pulmonary Disease Patient
11%
Obstructive Sleep Apnea
10%
Specific Intent
10%
Pulmonary Vascular
10%
Chronic Obstructive Pulmonary Disease
10%
Channel Activity
9%
Sensitive Membrane
8%
Hypoxia-sensitive
8%
Hes5
8%
Lung
7%
Pulmonary Vascular Resistance
6%
Sustained Hypoxia
6%
Knock-in Mouse Model
6%
Activator protein-1 (AP-1)
6%
Pulmonary Arterial Hypertension
6%
Normoxic
6%
Binding Activity
6%
Multifactorial Etiology
6%
Membrane Channels
6%
Lung Tissue
6%
Pharmacology, Toxicology and Pharmaceutical Science
Hypoxia
100%
Hypoxia-Induced Pulmonary Hypertension
83%
Transient Receptor Potential Channel
48%
Chronic Obstructive Lung Disease
27%
Mouse
26%
Vascular Remodeling
17%
Ion Channel
17%
Disease
12%
Pulmonary Hypertension
8%
Knockout Mouse
8%
Normal Human
8%
Sleep Disordered Breathing
6%
Medicine and Dentistry
Hypoxia
65%
Pulmonary Artery
50%
Smooth Muscle
50%
Hypoxia-Induced Pulmonary Hypertension
50%
Notch Signaling
29%
Transient Receptor Potential Channel
27%
Chronic Obstructive Pulmonary Disease
17%
Signal Transduction
11%
Vascular Remodeling
10%
Ion Channel
10%
Notch
9%
Disease
8%
Pulmonary Hypertension
5%
Membrane Channel
5%
Lung Vascular Resistance
5%
Binding Affinity
5%