Grant Details
Description
DESCRIPTION: The goal of this application is to identify the molecular mechanisms of perinatal HIV-1 transmission with the aim of developing relevant strategies for prevention. The investigator posits that there are specific molecular and biological properties of HIV-1 that include the functional domains in the gp120 region of Env and the p17 region of Gag that are critical determinants of perinatal HIV-1 transmission. Hypothesis-driven studies are proposed to; determine the molecular properties of viruses transmitted from an infected mother to her infant, identify and characterize the viral determinants associated with perinatal HIV-1 transmission, and determine the biological properties of viruses that are or are not transmitted from a mother to her infant.
Status | Finished |
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Effective start/end date | 4/1/97 → 5/31/06 |
Funding
- National Institutes of Health: $265,125.00
- National Institutes of Health: $106,050.00
- National Institutes of Health: $106,050.00
- National Institutes of Health: $106,050.00
ASJC
- Medicine(all)
- Immunology and Microbiology(all)
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