Grant Details
Description
The overall objective of this proposal is to continue the ongoing
Clinical Trial to compare the efficacy of Vitamin A (Retinol)
versus a placebo in the prevention of basal cell carcinoma or
cutaneous squamous cell carcinoma in participants diagnosed to
have multiple actinic keratoses. Our research plan involves a multidisciplinary cancer research
effort with the following specific aims: 1) To compare the incidence, frequency and time to
development of subsequent basal or squamous cell skin
cancers,
2) to measure the incidence, frequency and time to
development of other cancers,
3) To determine the frequency of and motivate protocol
compliance,
4) To determine the incidence, frequency, type and degree of
toxicity.
Clinical Trial to compare the efficacy of Vitamin A (Retinol)
versus a placebo in the prevention of basal cell carcinoma or
cutaneous squamous cell carcinoma in participants diagnosed to
have multiple actinic keratoses. Our research plan involves a multidisciplinary cancer research
effort with the following specific aims: 1) To compare the incidence, frequency and time to
development of subsequent basal or squamous cell skin
cancers,
2) to measure the incidence, frequency and time to
development of other cancers,
3) To determine the frequency of and motivate protocol
compliance,
4) To determine the incidence, frequency, type and degree of
toxicity.
| Status | Finished |
|---|---|
| Effective start/end date | 9/25/83 → 11/30/93 |
Funding
- National Institutes of Health
ASJC
- Medicine(all)
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