Scholarly Works per year
Scholarly Works per year
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Dive into the research topics where Vijay Gokhale is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Novel Brain-Penetrant, Small-Molecule Tubulin Destabilizers for the Treatment of Glioblastoma
Patrón, L. A., Yeoman, H., Wilson, S., Tang, N., Berens, M. E., Gokhale, V. & Suzuki, T. C., Feb 2024, In: Biomedicines. 12, 2, 406.Research output: Contribution to journal › Article › peer-review
Open Access -
Quindoline-derivatives display potent G-quadruplex-mediated antiviral activity against herpes simplex virus 1
Frasson, I., Soldà, P., Nadai, M., Tassinari, M., Scalabrin, M., Gokhale, V., Hurley, L. H. & Richter, S. N., Dec 2022, In: Antiviral Research. 208, 105432.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
In Silico Targeting of the Long Noncoding RNA MALAT1
François-Moutal, L., Miranda, V. G., Mollasalehi, N., Gokhale, V. & Khanna, M., Jun 10 2021, In: ACS Medicinal Chemistry Letters. 12, 6, p. 915-921 7 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Selective targeting of NaV1.7 via inhibition of the CRMP2-Ubc9 interaction reduces pain in rodents
Cai, S., Moutal, A., Yu, J., Chew, L. A., Isensee, J., Chawla, R., Gomez, K., Luo, S., Zhou, Y., Chefdeville, A., Madura, C., Perez-Miller, S., Bellampalli, S. S., Dorame, A., Scott, D. D., François-Moutal, L., Shan, Z., Woodward, T., Gokhale, V. & Hohmann, A. G. & 5 others, , Nov 10 2021, In: Science translational medicine. 13, 619, eabh1314.Research output: Contribution to journal › Article › peer-review
32 Scopus citations -
An allosteric modulator of RNA binding targeting the N-terminal domain of TDP-43 yields neuroprotective properties
Mollasalehi, N., Francois-Moutal, L., Scott, D. D., Tello, J. A., Williams, H., Mahoney, B., Carlson, J. M., Dong, Y., Li, X., Miranda, V. G., Gokhale, V., Wang, W., Barmada, S. J. & Khanna, M., Nov 20 2020, In: ACS Chemical Biology. 15, 11, p. 2854-2859 6 p.Research output: Contribution to journal › Article › peer-review
18 Scopus citations
Datasets
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CCDC 709587: Experimental Crystal Structure Determination
Vardanyan, R. (Creator), Vijay, G. (Creator), Nichol, G. S. (Creator), Liu, L. (Creator), Kumarasinghe, I. (Creator), Davis, P. (Creator), Vanderah, T. (Creator), Porreca, F. (Creator), Lai, J. (Creator) & Hruby, V. J. (Creator), Cambridge Crystallographic Data Centre, 2010
DOI: 10.5517/ccrtcxt, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccrtcxt&sid=DataCite
Dataset
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In vitro activity of a G-quadruplex-stabilizing small molecule that synergizes with Navitoclax to induce cytotoxicity in acute myeloid leukemia cells
Montoya, J. J. (Creator), Turnidge, M. A. (Creator), Wai, D. H. (Creator), Patel, A. R. (Contributor), Lee, D. W. (Creator), Gokhale, V. (Creator), Hurley, L. H. (Creator), Arceci, R. J. (Creator), Wetmore, C. (Creator) & Azorsa, D. O. (Creator), figshare, 2019
DOI: 10.6084/m9.figshare.c.4799331.v1, https://springernature.figshare.com/collections/In_vitro_activity_of_a_G-quadruplex-stabilizing_small_molecule_that_synergizes_with_Navitoclax_to_induce_cytotoxicity_in_acute_myeloid_leukemia_cells/4799331/1
Dataset
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CCDC 843705: Experimental Crystal Structure Determination
Raghunand, N. (Creator), Guntle, G. P. (Creator), Gokhale, V. (Creator), Nichol, G. S. (Creator), Mash, E. A. (Creator) & Jagadish, B. (Creator), Cambridge Crystallographic Data Centre, 2011
DOI: 10.5517/ccx9y9f, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccx9y9f&sid=DataCite
Dataset
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Crystal structure of R88A mutant of the NM23-H2 transcription factor
Dexheimer, T. S. (Contributor), Carey, S. S. (Contributor), Zuohe, S. (Contributor), Gokhale, V. M. (Contributor), Hu, X. (Contributor), Murata, L. B. (Contributor), Maes, E. M. (Contributor), Weichsel, A. (Contributor), Sun, D. (Contributor), Meuillet, E. J. (Contributor), Montfort, W. R. (Contributor), Hurley, L. H. (Contributor), Moréra, S. (Contributor), Lacombe, M.-L. (Contributor), Yingwu, X. (Contributor) & Joël Janin, G. L. A. (Contributor), Protein Data Bank (PDB), Sep 23 2008
DOI: 10.2210/pdb3BBC/pdb, https://www.wwpdb.org/pdb?id=pdb_00003bbc
Dataset
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Crystal structure of the NM23-H2 transcription factor complex with dinucleotide d(AG)
Dexheimer, T. S. (Contributor), Carey, S. S. (Contributor), Zuohe, S. (Contributor), Gokhale, V. M. (Contributor), Hu, X. (Contributor), Murata, L. B. (Contributor), Maes, E. M. (Contributor), Weichsel, A. (Contributor), Sun, D. (Contributor), Meuillet, E. J. (Contributor), Montfort, W. R. (Contributor), Hurley, L. H. (Contributor), Moréra, S. (Contributor), Lacombe, M.-L. (Contributor), Yingwu, X. (Contributor) & Joël Janin, G. L. A. (Contributor), Protein Data Bank (PDB), Sep 23 2008
DOI: 10.2210/pdb3BBB/pdb, https://www.wwpdb.org/pdb?id=pdb_00003bbb
Dataset