Scholarly Works per year
Scholarly Works per year
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Dive into the research topics where Timothy Marlowe is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Computational-based discovery of FAK FERM domain chemical probes that inhibit HER2-FAK cancer signaling
Stahl, E., Nott, R., Koessel, K., Cance, W. & Marlowe, T., Jun 1 2020, In: Chemical Biology and Drug Design. 95, 6, p. 584-599 16 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
Development of a fragment-based screening assay for the focal adhesion targeting domain using SPR and NMR
Alvarado, C., Stahl, E., Koessel, K., Rivera, A., Cherry, B. R., Pulavarti, S. V. S. R. K., Szyperski, T., Cance, W. & Marlowe, T., Sep 14 2019, In: Molecules. 24, 18, 3352.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
High resolution crystal structure of the FAK FERM domain reveals new insights on the Druggability of tyrosine 397 and the Src SH3 binding site
Marlowe, T., Dementiev, A., Figel, S., Rivera, A., Flavin, M. & Cance, W., May 20 2019, In: BMC Molecular and Cell Biology. 20, 1, 10.Research output: Contribution to journal › Article › peer-review
Open Access8 Scopus citations -
Mechanism of neem limonoids-induced cell death in cancer: Role of oxidative phosphorylation
Yadav, N., Kumar, S., Kumar, R., Srivastava, P., Sun, L., Rapali, P., Marlowe, T., Schneider, A., Inigo, J. R., O'Malley, J., Londonkar, R., Gogada, R., Chaudhary, A. K., Yadava, N. & Chandra, D., Jan 2016, In: Free Radical Biology and Medicine. 90, p. 261-271 11 p.Research output: Contribution to journal › Article › peer-review
9 Scopus citations -
Oncogenic receptor tyrosine kinases directly phosphorylate focal adhesion kinase (FAK) as a resistance mechanism to fak-kinase inhibitors
Marlowe, T. A., Lenzo, F. L., Figel, S. A., Grapes, A. T. & Cance, W. G., Dec 2016, In: Molecular Cancer Therapeutics. 15, 12, p. 3028-3039 12 p.Research output: Contribution to journal › Article › peer-review
21 Scopus citations
Grants
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Discovery of PPI inhibitors for the FAK FAT domain
Project: Research project
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Non-catalytic FAK inhibitors as novel therapeutics for lung fibrosis
Project: Research project
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Datasets
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Development of a High-Throughput Fluorescence Polarization Assay to Detect Inhibitors of the FAK–Paxillin Interaction
Marlowe, T. (Creator), Alvarado, C. (Creator), Rivera, A. (Creator), Lenzo, F. (Creator), Nott, R. (Creator), Bondugji, D. (Creator), Montoya, J. (Creator), Hurley, A. (Creator), Kaplan, M. (Creator), Capaldi, A. P. (Creator) & Cance, W. (Creator), SAGE Journals, 2019
DOI: 10.25384/sage.c.4665260, https://sage.figshare.com/collections/Development_of_a_High-Throughput_Fluorescence_Polarization_Assay_to_Detect_Inhibitors_of_the_FAK_Paxillin_Interaction/4665260
Dataset
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Development of a High-Throughput Fluorescence Polarization Assay to Detect Inhibitors of the FAK–Paxillin Interaction
Marlowe, T. (Creator), Alvarado, C. (Creator), Rivera, A. (Creator), Lenzo, F. (Creator), Nott, R. (Creator), Bondugji, D. (Creator), Montoya, J. (Creator), Hurley, A. (Creator), Kaplan, M. (Creator), Capaldi, A. P. (Creator) & Cance, W. (Creator), SAGE Journals, 2019
DOI: 10.25384/sage.c.4665260.v1, https://sage.figshare.com/collections/Development_of_a_High-Throughput_Fluorescence_Polarization_Assay_to_Detect_Inhibitors_of_the_FAK_Paxillin_Interaction/4665260/1
Dataset