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Collaborations and top research areas from the last five years
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Autoinhibition of cMyBP-C by its middle domains
Greenman, A. C., Sadler, R. L. & Harris, S. P., Mar 2025, In: Journal of Molecular and Cellular Cardiology. 200, p. 82-92 11 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Scopus citations -
Establishing a robust genetic sequencing and gene expression data library in cardiovascularly healthy cats
Kaplan, J. L., Rivas, V. N., Wouters, J. R., Vandewege, M. W., Harris, S. P. & Stern, J. A., Dec 2025, In: Scientific reports. 15, 1, 22051.Research output: Contribution to journal › Article › peer-review
Open Access1 Link opens in a new tab Scopus citations -
Mavacamten facilitates myosin head ON-to-OFF transitions and shortens thin filament length in relaxed mouse skeletal muscle
Kuehn, M. N., Engels, N. M., Nissen, D. L., Freundt, J. K., Ma, W., Harris, S. P., Irving, T. C., Linke, W. A. & Hessel, A. L., Oct 2025, In: Physiological reports. 13, 20, e70606.Research output: Contribution to journal › Article › peer-review
Open Access -
Myosin-binding protein C slows cardiac myofibril relaxation kinetics
Dvornikov, A. V. & Harris, S. P., Oct 1 2025, In: Journal of Physiology. 603, 19, p. 5351-5368 18 p.Research output: Contribution to journal › Article › peer-review
2 Link opens in a new tab Scopus citations -
Single Cell Transcriptomic Profiling of MYBPC3-Associated Hypertrophic Cardiomyopathy Across Species Reveals Conservation of Biological Process But Not Gene Expression
Ali, S. A., Perera, G., Laird, J., Batorsky, R., Maron, M. S., Rivas, V. N., Stern, J. A., Harris, S. & Chin, M. T., Jan 7 2025, In: Journal of the American Heart Association. 14, 1, e035780.Research output: Contribution to journal › Article › peer-review
Open Access4 Link opens in a new tab Scopus citations
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Molecular Mechanisms of Disease in a Novel Feline Model of Familial Hypertrophic
Harris, S. (PI)
Project: Research project
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Mechanisms of Thin Filament Regulation by Myosin Binding Protein-C
Harris, S. (PI)
Project: Research project
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Cut and paste of myosin binding protein-C in skeletal muscles
Harris, S. (PI)
Project: Research project
Datasets
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Precision medicine validation: identifying the MYBPC3 A31P variant with whole-genome sequencing in two Maine Coon cats with hypertrophic cardiomyopathy
Ontiveros, E. S. (Creator), Ueda, Y. (Creator), Harris, S. P. (Creator) & Stern, J. A. (Creator), figshare, 2018
DOI: 10.25384/sage.c.4342904, https://sage.figshare.com/collections/Precision_medicine_validation_identifying_the_i_MYBPC_i_3_A31P_variant_with_whole-genome_sequencing_in_two_Maine_Coon_cats_with_hypertrophic_cardiomyopathy/4342904
Dataset
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Precision medicine validation: identifying the MYBPC3 A31P variant with whole-genome sequencing in two Maine Coon cats with hypertrophic cardiomyopathy
Ontiveros, E. S. (Creator), Ueda, Y. (Creator), Harris, S. P. (Creator) & Stern, J. A. (Creator), figshare, 2018
DOI: 10.25384/sage.c.4342904.v1, https://sage.figshare.com/collections/Precision_medicine_validation_identifying_the_i_MYBPC_i_3_A31P_variant_with_whole-genome_sequencing_in_two_Maine_Coon_cats_with_hypertrophic_cardiomyopathy/4342904/1
Dataset
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Precision medicine validation: identifying the MYBPC3 A31P variant with whole-genome sequencing in two Maine Coon cats with hypertrophic cardiomyopathy
Ontiveros, E. S. (Creator), Ueda, Y. (Creator), Harris, S. P. (Creator) & Stern, J. A. (Creator), figshare, 2018
DOI: 10.25384/sage.c.4342904, https://sage.figshare.com/collections/Precision_medicine_validation_identifying_the_i_MYBPC_i_3_A31P_variant_with_whole-genome_sequencing_in_two_Maine_Coon_cats_with_hypertrophic_cardiomyopathy/4342904
Dataset
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Cardiac F-actin decorated with regulatory M-domain of cardiac myosin binding protein C
Risi, C. M. (Contributor), Villanueva, E. (Contributor), Belknap, B. (Contributor), Sadler, R. L. (Contributor), Harris, S. P. (Contributor), White, H. D. (Contributor) & Galkin, V. E. (Contributor), Protein Data Bank (PDB), Nov 23 2022
DOI: 10.2210/pdb7TIJ/pdb, https://www.wwpdb.org/pdb?id=pdb_00007tij
Dataset
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Cardiac thin filament decorated with C0C1 fragment of cardiac myosin binding protein C mode 1
Risi, C. (Contributor), Belknap, B. (Contributor), Forgacs-Lonart, E. (Contributor), Harris, S. P. (Contributor), Schröder, G. F. (Contributor), White, H. D. (Contributor) & Galkin, V. E. (Contributor), Protein Data Bank (PDB), Oct 10 2018
DOI: 10.2210/pdb6CXI/pdb, https://www.wwpdb.org/pdb?id=pdb_00006cxi
Dataset